CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11220
Family Name Sodium-dependent serotonin transporter and Alpha-2A adrenergic receptor ligand (3R,3aR)-7-methoxy-3-[[4-(naphthalen-2-ylmethyl)piperazin-1-yl]methyl]-3,3a-dihydrobenzo[g][2,1]benzoxazole family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00407599 Functional Category Bioactive
Superfamily Beta-lactamase and D(2) dopamine receptor Binder Superfamily 6
Class Class 4835

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Substance-P receptor ligand AGN-PC-02K8FR family 1 3
Sodium-dependent dopamine transporter and Sodium-dependent ser... 6 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 0
Peroxisome proliferator-activated receptor gamma ligand 2-etho... 6 2
Histamine H3 receptor ligand (NE)-N-[2-[2-(dimethylamino)ethox... 3 2


External ID

Functional Category

Molecule Name

CFAMM00407602 CHEMBL2112982 Bioactive (3R,3aR)-7-methoxy-3-[[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]methyl]-3,3a-dihydrobenzo[g][2,1]benzoxazole
CFAMM00407599 CHEMBL2112972 Bioactive (3R,3aR)-7-methoxy-3-[[4-(naphthalen-2-ylmethyl)piperazin-1-yl]methyl]-3,3a-dihydrobenzo[g][2,1]benzoxazole

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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