CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11224
Family Name Mitogen-activated protein kinase 14 inhibitor pyrimido-pyrimidine, 38 family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00407609 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 and Dipeptidyl peptidase 4 Binder Superfamily
Class Class 3679

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 16 295
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 5 2
Cannabinoid receptor 1 ligand SureCN675796 family 5 1
Translocator protein inhibitor N-butan-2-yl-4-(2-chlorophenyl)... 14 12
Mitogen-activated protein kinase 14 inhibitor pyrimido-pyrimid... 15 0
Proto-oncogene tyrosine-protein kinase Src and Fibroblast grow... 3 4
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 7 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand 6-(2-... 2 0


External ID

Functional Category

Molecule Name

CFAMM00407610 CHEMBL211426 Bioactive pyrimido-pyrimidine, 33
CFAMM00407609 CHEMBL378717 Bioactive pyrimido-pyrimidine, 38
CFAMM00407608 CHEMBL215651 Bioactive pyrimido-pyrimidine, 37
CFAMM00407612 CHEMBL211303 Bioactive pyrimido-pyrimidine, 39
CFAMM00407611 CHEMBL213836 Bioactive pyrimido-pyrimidine, 31

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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