CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11234
Family Name Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-[(2S,3S)-4-(4-chlorophenyl)-3-phenylbutan-2-yl]-2-methyl-2-phenoxypropanamide family
No. of Seeds 10 No. of Other Members 12
Family Centroid CFAMM00407672 Functional Category Bioactive
Superfamily C-C chemokine receptor type 1 and Cannabinoid receptor 2 Binder Superfamily
Class Class 2862

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase PLK1 Inhibitor On Fa... 16 138
Beta-3 adrenergic receptor Ligand Amibegron Family 8 46
Prothrombin and Tissue-type plasminogen activator inhibitor CH... 10 5
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 6 22
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 13 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 2 1
Plasmepsin-2 and Cathepsin D inhibitor N-[2-(1,3-benzodioxol-5... 4 0
Kappa-type opioid receptor ligand AGN-PC-03TFVP family 1 10
Cathepsin K and Cathepsin L1 inhibitor dipeptidyl nitrile, 16c... 1 0
Scytalone dehydratase inhibitor 2-cyano-N-[(1S,2R)-1-(2-cyanop... 5 0
Growth hormone secretagogue receptor type 1 ligand N-benzyl-2-... 5 19


External ID

Functional Category

Molecule Name

CFAMM00407687 CHEMBL385767 Bioactive N-[(2S,3S)-4-(4-chlorophenyl)-3-phenylbutan-2-yl]-2-(3-fluorophenoxy)-2-methylpropanamide
CFAMM00407679 CHEMBL219480 Bioactive SureCN3374706
CFAMM00407686 CHEMBL511245 Bioactive SureCN1895275
CFAMM00407678 CHEMBL218649 Bioactive 2-(4-chlorophenoxy)-N-[(2S,3S)-4-(4-chlorophenyl)-3-phenylbutan-2-yl]-2-methylpropanamide
CFAMM00407667 CHEMBL2113250 Bioactive 2-(4-chlorophenoxy)-N-[(2S,3S)-4-(4-chlorophenyl)-3-(3-fluorophenyl)butan-2-yl]-2-methylpropanamide
CFAMM00407684 CHEMBL385033 Bioactive 2-(3-chlorophenoxy)-N-[(2S,3S)-4-(4-chlorophenyl)-3-phenylbutan-2-yl]-2-methylpropanamide
CFAMM00407683 CHEMBL219188 Bioactive SureCN1899613
CFAMM00407666 CHEMBL2113253 Bioactive 2-(4-chlorophenoxy)-2-methyl-N-[(2S,3S)-3-phenyl-4-[4-(trifluoromethyl)phenyl]butan-2-yl]propanamide
CFAMM00407672 CHEMBL217862 Bioactive N-[(2S,3S)-4-(4-chlorophenyl)-3-phenylbutan-2-yl]-2-methyl-2-phenoxypropanamide
CFAMM00407674 CHEMBL466244 Bioactive SureCN1896440

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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