CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11240
Family Name Mu-type opioid receptor and Kappa-type opioid receptor ligand (E)-N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]-3-(3-nitrophenyl)prop-2-enamide family
No. of Seeds 9 No. of Other Members 2
Family Centroid CFAMM00407717 Functional Category Bioactive
Superfamily Nalfurafine Hcl Superfamily
Class Class 66

Cousin Family NamesSeedsMembers
u-type opioid receptor ligand opiate analog Buprenorphine Family 78 234
u-type opioid receptor ligand opiate opiate analog Oxymorphone... 22 105
Nalfurafine Hcl family 33 107
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 32 30
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 6 1
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 16 10
Kappa-type opioid receptor Ligand Morphinan Cyclic Imine Analo... 20 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 13 5
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 28 2
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Delta-type opioid receptor and Kappa-type opioid receptor liga... 6 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 18 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 9 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 7 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 3
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 8 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 7 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 10 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 0
Mu-type opioid receptor and Gastrin/cholecystokinin type B rec... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00407717 CHEMBL454018 Bioactive (E)-N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]-3-(3-nitrophenyl)prop-2-enamide
CFAMM00407723 CHEMBL2437062 Bioactive (E)-N-[(4R,4aR,7R,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]-3-(3-nitrophenyl)prop-2-enamide
CFAMM00407722 CHEMBL2113308 Bioactive CHEMBL2113308
CFAMM00407721 CHEMBL2437067 Bioactive (E)-N-[(4R,4aR,7R,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]-3-(3-nitrophenyl)prop-2-enamide
CFAMM00407720 CHEMBL448145 Bioactive (E)-N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]-3-(2-nitrophenyl)prop-2-enamide
CFAMM00407725 CHEMBL449561 Bioactive (E)-N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]-N-methyl-3-(3-nitrophenyl)prop-2-enamide
CFAMM00407718 CHEMBL417535 Bioactive (E)-N-[(4R,4aS,7R,7aR)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]-3-(4-nitrophenyl)prop-2-enamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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