CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11246
Family Name Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN1432327 family
No. of Seeds 11 No. of Other Members 4
Family Centroid CFAMM00404024 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-methoxy-2-[(4-methoxyphenyl)ethynyl]adenosine Superfamily
Class Class 1289

Cousin Family NamesSeedsMembers
Pigment epithelium-derived factor Inhibitor Adpedr Family 2 112
Adenosine receptor A3 Ligand CF101 Family 24 560
Poly [ADP-ribose] polymerase 1 Inhibitor EB-47 Family 17 41
Heat shock protein HSP 90-alpha Inhibitor 8-benzo[1,3]dioxol-,... 5 83
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 2 7
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 7 72
Adenosine receptor A1 and Adenosine receptor A2a Ligand GW-328... 26 94
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 21 57
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-[(4-... 15 9
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(3''... 2 3
Adenosine receptor A2a and Adenosine receptor A3 Ligand 2-(3''... 8 10
Inositol 1,4,5-trisphosphate receptor type 3 Ligand 5'-deoxy-5... 11 8
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 2 9
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 3 0
Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) ... 24 9
Adenosine receptor A3 ligand SureCN6211758 family 5 10
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 4
Adenosine receptor A1 ligand N-[(2R,3R,4R,5R)-5-[6-(cyclopenty... 3 2
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 6 17
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 2 0
Adenosine receptor A3 and Adenosine receptor A1 ligand (1S,2R,... 6 0
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 7 4
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 2 10
Adenosine receptor A1 ligand 2-[4-[[2-[4-[[9-[(3R,4S,5R)-3,4-d... 14 0
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 2 0
Adenosine receptor A3 and Adenosine receptor A1 ligand (2R,3R,... 1 0
Adenosine receptor A1 ligand 2-[4-[[2-[4-[[9-[(3R,4S,5R)-3,4-d... 1 0
Adenosine receptor A1 and Adenosine receptor A2b ligand (2R,3R... 1 0
Adenosine receptor A2a and Adenosine receptor A1 ligand (2R,3R... 3 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00407815 CHEMBL388194 Bioactive (2S,3S,4R,5R)-5-[6-[4-[2-(1,3-benzodioxol-5-ylamino)-2-oxoethoxy]anilino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00407814 CHEMBL388193 Bioactive (2S,3S,4R,5R)-5-[6-[4-[2-(4-bromoanilino)-2-oxoethoxy]anilino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
CFAMM00407819 CHEMBL604834 Bioactive (2S,3S,4R)-3,4-dihydroxy-5-[6-(4-methoxyanilino)purin-9-yl]oxolane-2-carboxylic acid
CFAMM00407818 CHEMBL603990 Bioactive (2S,3S,4R)-N-ethyl-3,4-dihydroxy-5-[6-(4-methoxyanilino)purin-9-yl]oxolane-2-carboxamide
CFAMM00407817 CHEMBL226244 Bioactive (2S,3S,4R,5R)-5-[6-[4-[2-(3,4-dimethoxyanilino)-2-oxoethoxy]anilino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27265 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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