CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11264
Family Name C-X-C chemokine receptor type 2 ligand 3-[[3,4-dioxo-2-(pentan-3-ylamino)cyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide family
No. of Seeds 6 No. of Other Members 6
Family Centroid CFAMM00407960 Functional Category Bioactive
Superfamily Dihydroorotate dehydrogenase Inhibitor Antimycin A Superfamily
Class Class 517

Cousin Family NamesSeedsMembers
Mucosal addressin cell adhesion molecule 1 Inhibitor PF-005476... 64 96
C-X-C chemokine receptor type 2 and C-X-C chemokine receptor t... 9 4
C-X-C chemokine receptor type 2 and C-X-C chemokine receptor t... 3 7
C-X-C chemokine receptor type 2 ligand 3-[[2-[[(1R)-1-(3-fluor... 14 0


External ID

Functional Category

Molecule Name

CFAMM00407963 CHEMBL211468 Bioactive 3-[(2-anilino-3,4-dioxocyclobuten-1-yl)amino]-2-hydroxy-N,N-dimethylbenzamide
CFAMM00407968 CHEMBL375175 Bioactive 3-[[3,4-dioxo-2-(propan-2-ylamino)cyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
CFAMM00407961 CHEMBL214162 Bioactive 3-[[2-(cyclopentylamino)-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
CFAMM00407960 CHEMBL214047 Bioactive 3-[[3,4-dioxo-2-(pentan-3-ylamino)cyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
CFAMM00407966 CHEMBL387431 Bioactive 3-[(2-anilino-3,4-dioxocyclobuten-1-yl)amino]-5-chloro-2-hydroxy-N,N-dimethylbenzamide
CFAMM00407964 CHEMBL213130 Bioactive 3-[[2-(cyclohexylamino)-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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