CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11270
Family Name Substance-P receptor ligand AGN-PC-073QYE family
No. of Seeds 6 No. of Other Members 11
Family Centroid CFAMM00407989 Functional Category Bioactive
Superfamily Substance-P receptor and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily 3
Class Class 3563

Cousin Family NamesSeedsMembers
Glutathione S-transferase Inhibitor Praziquantel Family 5 167
DNA Binder Procarbazine Family 8 358
Peripheral carotid chemoreceptor Ligand Doxapram Family 4 36
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
Neuromedin-K receptor Ligand Osanetant Family 38 192
Substance-P receptor Ligand Orvepitant Family 11 46
5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Poly(ADP-ribose) glycohydrolase Inhibitor N-bis-(3-phenyl-prop... 3 7
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Tic... 11 31
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
D(2) dopamine receptor and D(3) dopamine receptor Ligand ST-19... 5 27
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 44 28
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
5-hydroxytryptamine receptor 2A Ligand N-(1-(3-bromobenzyl)pip... 6 10
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand N-(3-... 1 7
Substance-P receptor ligand AGN-PC-00FJ8P family 6 10
C-C chemokine receptor type 5 ligand AC1L9USC family 3 2
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-2-[... 14 4
Substance-P receptor ligand AGN-PC-075NRR family 2 1
Neuromedin-K receptor ligand SureCN2477089 family 2 4
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (2S... 16 24
Sigma non-opioid intracellular receptor 1 ligand 2-(3-bromophe... 5 1
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 7 3
Substance-P receptor ligand (3S,4S)-N-[[3,5-bis(trifluoromethy... 8 9
Oxytocin receptor and Vasopressin V2 receptor ligand (2R)-2-(2... 4 2
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 4 inhibitor (2... 3 10
Substance-P receptor and Potassium voltage-gated channel subfa... 4 7
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 5
Kinesin-like protein KIF11 and Potassium voltage-gated channel... 4 1
Substance-P receptor ligand (3R,4R)-1-(1-acetylpiperidine-4-ca... 9 1
Substance-P receptor and Potassium voltage-gated channel subfa... 5 0
C-C chemokine receptor type 2 ligand (2S)-N-[[3,5-bis(trifluor... 1 0
C-C chemokine receptor type 2 ligand (1S,3R)-N-[[3-fluoro-5-(t... 22 27
Histamine H3 receptor ligand N-ethyl-3-fluoro-3-[3-fluoro-4-(p... 3 0
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 3 1
C-C motif chemokine 2 inhibitor (1S,3R)-N-[[3,5-bis(trifluorom... 1 0
Nociceptin receptor and Kappa-type opioid receptor ligand Pipe... 1 0
Substance-P receptor and Potassium voltage-gated channel subfa... 6 0
Substance-P receptor ligand AGN-PC-03I9DJ family 3 0
Substance-P receptor and Potassium voltage-gated channel subfa... 5 1
Kappa-type opioid receptor ligand SureCN5629426 family 3 2
C-C chemokine receptor type 2 ligand N-[[3-fluoro-5-(trifluoro... 2 1
Melanocortin receptor 4 and Melanocortin receptor 3 ligand (2S... 2 0
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 1
C-C chemokine receptor type 2 ligand (1S,3R)-N-[[3,5-bis(trifl... 8 8
Muscarinic acetylcholine receptor M3 ligand N-[[4-fluoro-3-[3-... 3 0
C-C chemokine receptor type 2 ligand (2S)-N-[[3,5-bis(trifluor... 1 1
C-C motif chemokine 2 inhibitor (1S,3R)-3-[(4-amino-2,3-dihydr... 1 0
C-C motif chemokine 2 inhibitor (1S,3R)-N-[[3,5-bis(trifluorom... 1 0
Substance-P receptor ligand AGN-PC-074VYH family 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00407995 CHEMBL2115007 Bioactive CHEMBL51893
CFAMM00407986 CHEMBL49176 Bioactive AGN-PC-03NGZY
CFAMM00407991 CHEMBL300014 Bioactive AGN-PC-03I9BS
CFAMM00407996 CHEMBL2115006 Bioactive AGN-PC-03I9DW
CFAMM00407989 CHEMBL295685 Bioactive AGN-PC-073QYE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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