CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11279
Family Name Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 inhibitor CHEMBL261386 family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00408047 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 and Prothrombin Binder Superfamily
Class Class 3039

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
Tubulin beta chain Inhibitor Mebendazole Family 12 84
BIBT986 family 7 96
CC-486 family 7 103
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Integrin alpha-V and Integrin beta-3 Inhibitor SB-223245 Family 27 36
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Telomerase reverse transcriptase Inhibitor NSC-745794 Family 3 1
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-57893 Family 3 8
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
Poly [ADP-ribose] polymerase 1 inhibitor 2-(3-chlorophenyl)-1H... 4 38
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... 9 10
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1801305 ... 2 0
Mitogen-activated protein kinase 9 and MAP kinase-activated pr... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 9 4
Serine/threonine-protein kinase Chk2 inhibitor SureCN3922132 f... 3 2
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5
Type-1 angiotensin II receptor ligand 7-methyl-N-(2-phenylethy... 2 10
Cyclin-dependent kinase 2 and Serine/threonine-protein kinase ... 2 2
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Prostaglandin E synthase inhibitor 2-(2-chloro-6-fluorophenyl)... 9 1
Prostaglandin E synthase inhibitor AGN-PC-00EMT0 family 7 3
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1
Prostaglandin E synthase inhibitor AGN-PC-04SSMB family 6 0
Prostaglandin E synthase inhibitor AGN-PC-07CRKH family 1 0
Poly [ADP-ribose] polymerase 1 inhibitor 2-[4-(5-sulfanylidene... 1 1
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Sonic hedgehog protein and Cytochrome P450 2C9 inhibitor AGN-P... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00408047 CHEMBL261386 Bioactive CHEMBL261386
CFAMM00408046 CHEMBL272424 Bioactive CHEMBL272424

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27260 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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