CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11284
Family Name Melanocortin receptor 4 ligand N-[(2R)-3-(2,4-dichlorophenyl)-1-[4-[3-[[2-(2-methoxyphenyl)ethylamino]methyl]pyridin-2-yl]piperazin-1-yl]-1-oxopropan-2-yl]acetamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00408095 Functional Category Bioactive
Superfamily Melanocortin receptor 4 and Ras-related protein Rab-9A Binder Superfamily
Class Class 974

Cousin Family NamesSeedsMembers
Smoothened homolog Inhibitor LDE225 Family 3 76
Proto-oncogene tyrosine-protein kinase Src Inhibitor PD166285 ... 6 70
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
Potassium voltage-gated channel subfamily H member 2 Ligand Be... 22 56
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 3
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Liver carboxylesterase 1 Inhibitor SM-32504 Family 3 28
Melanin-concentrating hormone receptor 1 ligand N-[1-(1,3-benz... 2 5
Rho-associated protein kinase 1 and cAMP-dependent protein kin... 1 11
C-C chemokine receptor type 4 ligand [4-[4-[(2,4-dichloropheny... 4 4
Histamine H3 receptor ligand [1-[(2-aminopyridin-4-yl)methyl]-... 2 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 1
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 2 5
Hepatocyte growth factor receptor ligand [4-[6-amino-5-[1-(2,6... 5 1
Proto-oncogene tyrosine-protein kinase Src and Fibroblast grow... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00408096 CHEMBL378046 Bioactive 3-amino-N-[(2R)-3-(2,4-dichlorophenyl)-1-[4-[3-[[2-(2-methoxyphenyl)ethylamino]methyl]pyridin-2-yl]piperazin-1-yl]-1-oxopropan-2-yl]propanamide
CFAMM00408095 CHEMBL211742 Bioactive N-[(2R)-3-(2,4-dichlorophenyl)-1-[4-[3-[[2-(2-methoxyphenyl)ethylamino]methyl]pyridin-2-yl]piperazin-1-yl]-1-oxopropan-2-yl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26373 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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