CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11293
Family Name Suppressor of tumorigenicity 14 protein and Plasminogen inhibitor SureCN6874294 family
No. of Seeds 10 No. of Other Members 15
Family Centroid CFAMM00408140 Functional Category Bioactive
Superfamily Suppressor of tumorigenicity 14 protein and Trypsin-1 Binder Superfamily
Class Class 1271

Cousin Family NamesSeedsMembers
Suppressor of tumorigenicity 14 protein and Prothrombin Inhibi... 4 126
Suppressor of tumorigenicity 14 protein Inhibitor 3-tapap Family 15 39
Trypsin Inhibitor Benzamidrazone Analogue Family 16 6
Coagulation factor X inhibitor (6S,8aS)-2-benzhydrylsulfonyl-N... 5 5
Plasminogen and Plasma kallikrein inhibitor CHEMBL2016864 family 9 16
Coagulation factor X and Trypsin-1 inhibitor SureCN6161266 family 2 28
B1 bradykinin receptor ligand N-[2-[4-(4,5-dihydro-1H-imidazol... 2 0
Plasminogen and Trypsin-1 inhibitor CHEMBL2315239 family 13 1
Growth hormone secretagogue receptor type 1 ligand 2-amino-2-m... 4 2
Suppressor of tumorigenicity 14 protein and Prothrombin inhibi... 2 5
Suppressor of tumorigenicity 14 protein and Prothrombin inhibi... 4 0


External ID

Functional Category

Molecule Name

CFAMM00408140 CHEMBL379194 Bioactive SureCN6874294
CFAMM00408139 CHEMBL437307 Bioactive 3-amino-N-[3-[[(2S)-1-[4-(3-aminopropyl)piperidin-1-yl]-3-(3-carbamimidoylphenyl)-1-oxopropan-2-yl]sulfamoyl]phenyl]propanamide
CFAMM00408151 CHEMBL379068 Bioactive 3-amino-N-[3-[[(2S)-3-(3-carbamimidoylphenyl)-1-[4-[3-(diaminomethylideneamino)propyl]piperidin-1-yl]-1-oxopropan-2-yl]sulfamoyl]phenyl]propanamide
CFAMM00408150 CHEMBL378657 Bioactive 3-amino-N-[3-[[(2S)-3-(3-carbamimidoylphenyl)-1-[4-[2-(diaminomethylideneamino)ethyl]piperidin-1-yl]-1-oxopropan-2-yl]sulfamoyl]phenyl]propanamide
CFAMM00408143 CHEMBL461870 Bioactive SureCN8187911
CFAMM00408136 CHEMBL444411 Bioactive SureCN8197768
CFAMM00408149 CHEMBL380221 Bioactive N-[4-[[(2S)-3-(3-carbamimidoylphenyl)-1-[4-[2-(diaminomethylideneamino)ethyl]piperidin-1-yl]-1-oxopropan-2-yl]sulfamoyl]phenyl]-3-(diaminomethylideneamino)propanamide
CFAMM00408141 CHEMBL378192 Bioactive N-[3-[[(2S)-3-(3-carbamimidoylphenyl)-1-[4-[2-(diaminomethylideneamino)ethyl]piperidin-1-yl]-1-oxopropan-2-yl]sulfamoyl]phenyl]-3-(diaminomethylideneamino)propanamide
CFAMM00408134 CHEMBL212014 Bioactive 4-amino-N-[3-[[(2S)-1-[4-(2-aminoethyl)piperidin-1-yl]-3-(3-carbamimidoylphenyl)-1-oxopropan-2-yl]sulfamoyl]phenyl]butanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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