CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1130
Family Name Tryptase alpha/beta-1 and Tryptase delta inhibitor AGN-PC-074XX2 family
No. of Seeds 5 No. of Other Members 6
Family Centroid CFAMM00319776 Functional Category Bioactive
Superfamily Alpha-2C adrenergic receptor and Alpha-2A adrenergic receptor Binder Superfamily
Class Class 1691

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand A-317920 Family 9 240
Substance-K receptor ligand 5-chloro-N-[1-[[(2S)-5-[4-(oxan-4-... 2 4
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-(benze... 3 14
Prostaglandin E2 receptor EP4 subtype ligand SureCN5653729 family 3 2


External ID

Functional Category

Molecule Name

CFAMM00319770 CHEMBL111643 Bioactive AGN-PC-074XRH
CFAMM00319776 CHEMBL112049 Bioactive AGN-PC-074XX2
CFAMM00319779 CHEMBL113452 Bioactive AGN-PC-074XT7
CFAMM00319778 CHEMBL324622 Bioactive 2-[4-[2-[5-[2-[4-(5-carbamimidoyl-1-benzofuran-2-carbonyl)piperazin-1-yl]-2-oxoethoxy]cyclooctyl]oxyacetyl]piperazine-1-carbonyl]-1-benzofuran-5-carboximidamide
CFAMM00319771 CHEMBL322345 Bioactive AGN-PC-074XRI

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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