CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11302
Family Name Melanin-concentrating hormone receptor 1 ligand AGN-PC-0762XZ family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00408185 Functional Category Bioactive
Superfamily Substance-P receptor and C-C chemokine receptor type 3 Binder Superfamily
Class Class 2044

Cousin Family NamesSeedsMembers
5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Pan-DAC Inhibitor AR-42 Family 21 153
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Androgen receptor Ligand YM-175735 Family 30 129
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Acetylcholinesterase inhibitor AGN-PC-07ZFTY family 1 0
Cathepsin K and Cathepsin B inhibitor AGN-PC-01Z23J family 2 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
Melanin-concentrating hormone receptor 1 ligand 1-[[4-[4-(3-cy... 14 23
Melanin-concentrating hormone receptor 1 ligand 1-[2-[4-(3-cya... 3 2
Melanin-concentrating hormone receptor 1 ligand AGN-PC-075BLN ... 2 1
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 0
Delta-type opioid receptor and Potassium voltage-gated channel... 3 2
Transient receptor potential cation channel subfamily V member... 9 38
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
Substance-P receptor and Potassium voltage-gated channel subfa... 5 0
Nociceptin receptor and Mu-type opioid receptor ligand N,N-dim... 5 4
Melanin-concentrating hormone receptor 1 ligand SureCN13655018... 6 23
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Melanin-concentrating hormone receptor 1 ligand SureCN13918038... 6 1
Cannabinoid receptor 2 ligand 1-adamantyl-(5-fluoro-2,3-dihydr... 4 7
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
5-hydroxytryptamine receptor 7 ligand 2-[4-[4-(2-oxo-1,3,4,5-t... 1 0
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 4 0
Somatostatin receptor type 1 ligand AGN-PC-078XL6 family 9 9
Phospholipase D1 and Phospholipase D2 inhibitor N-[(2S)-1-[4-(... 3 5
D(1A) dopamine receptor and D(3) dopamine receptor ligand 1-[4... 1 0
Melanin-concentrating hormone receptor 1 ligand AGN-PC-0762SF ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00408187 CHEMBL380371 Bioactive AGN-PC-00RX3K
CFAMM00408186 CHEMBL212265 Bioactive AGN-PC-02VUKT
CFAMM00408185 CHEMBL377321 Bioactive AGN-PC-0762XZ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26831 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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