CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11312
Family Name Glutamate receptor ionotropic, NMDA 2B ligand 2-[[4-(4-chlorophenoxy)piperidin-1-yl]-hydroxymethylidene]-1,3-dihydrobenzimidazole-5,6-dione family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00408274 Functional Category Bioactive
Superfamily Glutamate receptor ionotropic, NMDA 2B and Histamine H1 receptor Binder Superfamily
Class Class 1049

Cousin Family NamesSeedsMembers
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 3 23
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 50 17
Neuropeptide Y receptor type 5 and Alpha-1A adrenergic recepto... 8 2
Survival motor neuron protein inhibitor CHEMBL1379159 family 1 10
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
Coagulation factor X and Cationic trypsin inhibitor AGN-PC-075... 26 7
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 3
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0
Corticotropin-releasing factor receptor 1 ligand AGN-PC-009TSL... 3 3
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1
Histamine H3 receptor ligand AGN-PC-075YXY family 1 4
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 4 11
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 12 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 11 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 5
5-hydroxytryptamine receptor 1A and Gonadotropin-releasing hor... 3 0
5-hydroxytryptamine receptor 1A ligand AGN-PC-04UH85 family 2 3
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00408275 CHEMBL220474 Bioactive 2-[[4-(4-fluorophenoxy)piperidin-1-yl]-hydroxymethylidene]-1,3-dihydrobenzimidazole-5,6-dione
CFAMM00408274 CHEMBL375615 Bioactive 2-[[4-(4-chlorophenoxy)piperidin-1-yl]-hydroxymethylidene]-1,3-dihydrobenzimidazole-5,6-dione
CFAMM00408273 CHEMBL212484 Bioactive [4-(4-chlorophenoxy)piperidin-1-yl]-(6-hydroxy-1H-benzimidazol-2-yl)methanone
CFAMM00408271 CHEMBL380179 Bioactive [4-(4-fluorophenoxy)piperidin-1-yl]-(6-hydroxy-1H-benzimidazol-2-yl)methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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