CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11325
Family Name Cathepsin K and Cathepsin L1 inhibitor (2R)-N-(cyanomethyl)-4-methyl-2-[3-[3-[2-(piperazin-1-ylmethyl)-1,3-thiazol-4-yl]phenyl]phenyl]pentanamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00250075 Functional Category Bioactive
Superfamily Phosphoribosylaminoimidazolecarboxamide formyltransferase Inhibitor NSC-26699 Superfamily
Class Class 2131

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor RWJ-50353 Family 11 95
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-me... 2 45
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Cyclin-dependent kinase 5 Inhibitor 3-(2-phenylthiazol-4-yl)qu... 2 44
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 4 3
Transient receptor potential cation channel subfamily V member... 1 17
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Deoxycytidine kinase inhibitor N-[(1S,3S)-3-(4-amino-5-fluoro-... 2 5
Dipeptidyl peptidase 1 inhibitor (2S)-2-amino-N-[(1S)-2-(1,3-b... 1 1
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 2 5
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Histone deacetylase 1 and Histone deacetylase 2 inhibitor 7-[4... 3 0
Cathepsin K and Cathepsin S inhibitor N-[1-(cyanomethylcarbamo... 2 1
Protease and Capsid scaffolding protein inhibitor AC1LAC7K family 2 5
Coagulation factor X and Prothrombin inhibitor (2S)-2-(benzyls... 4 4
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 13
Prothrombin inhibitor (3R,6S,8aS)-N-[5-(diaminomethylideneamin... 2 3
Prothrombin and Cationic trypsin inhibitor 2-ketobenzothiazole... 3 3
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 16
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor th... 1 3
Serine/threonine-protein kinase Chk1 inhibitor 2-(1H-indol-5-y... 2 2
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-benzothiop... 4 6
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-phenyl-1,3-t... 3 4
Cathepsin K and Cathepsin S inhibitor (1R,2R)-2-[4-(1,3-benzot... 1 4
Suppressor of tumorigenicity 14 protein and Serine protease he... 6 0
D(3) dopamine receptor and D(2) dopamine receptor ligand [4-[2... 5 5
D(3) dopamine receptor and D(2) dopamine receptor ligand [4-[2... 6 5
Cholinesterase and Acetylcholinesterase inhibitor 3-[ethyl-[3-... 6 9
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 8 1
Serine/threonine-protein kinase Chk1 inhibitor 2-(1,3-dihydroi... 2 5
Cathepsin K inhibitor N-(cyanomethyl)-5,5-difluoro-2-[2-methyl... 1 0
MAP kinase-activated protein kinase 2 inhibitor 2-[(4,4-dimeth... 11 11
Neuropeptide Y receptor type 5 ligand 2-(dimethylamino)-1-[4-[... 10 5
Neuropeptide Y receptor type 5 ligand 1-[4-[[(9-fluoro-5,6-dih... 11 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27398 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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