CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11329
Family Name Protein farnesyltransferase alpha subunit and Protein farnesyltransferase beta subunit inhibitor Sulfonamide 12d family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00131195 Functional Category Bioactive
Superfamily Protein farnesyltransferase beta subunit and Protein farnesyltransferase alpha subunit Binder Superfamily
Class Class 2000

Cousin Family NamesSeedsMembers
Farnesyltransferase beta subunit, putative Inhibitor BMS214662... 11 65
Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 13 55
Farnesyltransferase beta subunit, putative and Protein farnesy... 20 81
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-cyanobenzyl... 14 13
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-aminobenzyl... 3 6
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 2-(4-... 8 25
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
Protein farnesyltransferase subunit beta Inhibitor BMS-316810 ... 11 18
Farnesyltransferase beta subunit, putative and Protein farnesy... 12 4
Motilin receptor and Growth hormone secretagogue receptor type... 2 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 2
Cytochrome P450 11B2, mitochondrial and Cytochrome P450 11B1, ... 1 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 9 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Protein farnesyltransferase alpha subunit and Protein farnesyl... 2 0
Cannabinoid receptor 2 ligand 4-[[2-tert-butyl-1-(cyclohexylme... 2 0
Dipeptidyl peptidase 4 inhibitor 7-(aminomethyl)-6-(2-chloroph... 2 5
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-a]pyridine der... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00408448 CHEMBL213330 Bioactive Sulfonamide 12c

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26187 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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