CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1133
Family Name Beta-1 adrenergic receptor and Beta-2 adrenergic receptor ligand 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)phenoxy]propan-2-ol family
No. of Seeds 14 No. of Other Members 2
Family Centroid CFAMM00319846 Functional Category Bioactive
Superfamily Beta-lactamase and Beta-2 adrenergic receptor Binder Superfamily
Class Class 1249

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand 4-(3-phenoxy-propyl)-1h-imidazole... 26 142
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 7 16
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 4 18
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 6 7
Beta-1 adrenergic receptor ligand 1-[4-[2-(5-bromo-1H-imidazol... 3 8
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 1 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
D(2) dopamine receptor ligand AGN-PC-07C1V6 family 2 3
Potassium-transporting ATPase alpha chain 1 and Potassium-tran... 2 11


External ID

Functional Category

Molecule Name

CFAMM00319853 CHEMBL2052005 Bioactive (2S)-1-(2-ethoxyethylamino)-3-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)phenoxy]propan-2-ol
CFAMM00319846 CHEMBL11671 Bioactive 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)phenoxy]propan-2-ol
CFAMM00319845 CHEMBL177765 Bioactive 1-[1-(3,4-dimethoxyphenyl)propan-2-ylamino]-3-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)phenoxy]propan-2-ol
CFAMM00319851 CHEMBL177860 Bioactive 1-[[1-(3,4-dimethoxyphenyl)-2-methylpropan-2-yl]amino]-3-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)phenoxy]propan-2-ol
CFAMM00319844 CHEMBL11396 Bioactive 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-[2-methyl-4-(5-thiophen-2-yl-1H-imidazol-2-yl)phenoxy]propan-2-ol
CFAMM00319850 CHEMBL11205 Bioactive 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-[4-[(5-thiophen-2-yl-1H-imidazol-2-yl)methyl]phenoxy]propan-2-ol
CFAMM00319843 CHEMBL434360 Bioactive SureCN10554980
CFAMM00319849 CHEMBL415970 Bioactive 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-[4-[2-(5-thiophen-2-yl-1H-imidazol-2-yl)ethyl]phenoxy]propan-2-ol
CFAMM00319854 CHEMBL11431 Bioactive 1-[2-chloro-4-(5-thiophen-2-yl-1H-imidazol-2-yl)phenoxy]-3-[2-(3,4-dimethoxyphenyl)ethylamino]propan-2-ol
CFAMM00319847 CHEMBL11178 Bioactive 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-[5-(5-thiophen-2-yl-1H-imidazol-2-yl)pyridin-2-yl]oxypropan-2-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



53683 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543