CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11338
Family Name cAMP-dependent protein kinase catalytic subunit beta and cAMP-dependent protein kinase catalytic subunit gamma inhibitor N-[(1s)-2-Amino-1-(2,4-Dichlorobenzyl)ethyl]-5-[2-(Methylamino)pyrimidin-4-Yl]thiophene-2-Carboxamide family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00327527 Functional Category Bioactive
Superfamily Cruzipain and Polycystin-2 Binder Superfamily
Class Class 3131

Cousin Family NamesSeedsMembers
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
Rho-associated protein kinase 2 and cAMP-dependent protein kin... 3 5
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-1-phenyl-5-(4... 3 9
Dipeptidyl peptidase 8 and Dipeptidyl peptidase 9 inhibitor AG... 3 3
Serine/threonine-protein kinase Chk1 inhibitor SureCN13010134 ... 7 29
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
Thyroid hormone receptor beta and Ferritin light chain ligand ... 3 10
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QJ7P family 2 0
Protein kinase C zeta type and Inhibitor of nuclear factor kap... 1 6
C-C chemokine receptor type 4 ligand [4-[4-[(2,4-dichloropheny... 4 4
P2X purinoceptor 7 inhibitor SureCN110930 family 2 0
NAD-dependent protein deacetylase sirtuin-2 and NAD-dependent ... 8 12
Tyrosine-protein kinase Lck inhibitor AGN-PC-074MSE family 18 2
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-00A4QJ family 12 6
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 5 0
Neuropeptides B/W receptor type 1 ligand [4-(5-chloropyridin-2... 5 3


External ID

Functional Category

Molecule Name

CFAMM00408482 CHEMBL379507 Bioactive AGN-PC-00S0XP

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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