CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11339
Family Name Melanin-concentrating hormone receptor 1 ligand 3-[6-[3-(dimethylamino)pyrrolidin-1-yl]pyridin-3-yl]-7-phenoxychromen-4-one family
No. of Seeds 1 No. of Other Members 13
Family Centroid CFAMM00408501 Functional Category Bioactive with Natural Product
Superfamily Melanin-concentrating hormone receptor 1 and Adenosine receptor A1 Binder Superfamily
Class Class 1163

Cousin Family NamesSeedsMembers
Smoothened homolog Inhibitor LDE225 Family 3 76
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
5-hydroxytryptamine receptor 1A Ligand Sun N4057 Family 2 86
Aromatase Inhibitor 2-phenyl-3-pyridin-4-ylmethylene-chroman-4... 3 30
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
MO15-related protein kinase Pfmrk Inhibitor WR-289010 Family 2 506
Oxytocin receptor and Vasopressin V1a receptor Ligand L-372662... 31 23
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Potassium voltage-gated channel subfamily H member 2 and Neuro... 3 4
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 20 28
Aldo-keto reductase family 1 member B10 and Aldose reductase i... 4 13
Acetylcholinesterase and Butyrylcholinesterase inhibitor [3-[[... 3 68
Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N... 8 10
Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N... 4 0
Melanin-concentrating hormone receptor 1 ligand 3-[6-[3-(dimet... 14 6
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Serine/threonine-protein kinase pim-1 inhibitor (2Z)-6-methoxy... 1 5
Histamine H1 receptor ligand 2-(3-hydroxy-6-oxoxanthen-9-yl)-5... 3 10
Aurora kinase B and Aurora kinase A inhibitor 2-fluoro-6-metho... 2 0
Acetylcholinesterase and Cholinesterase inhibitor 5-methoxy-7-... 1 18
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 1
Aromatase inhibitor isoflavone deriv. 5m family 1 0
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 4
Integrin beta-3 and Integrin alpha-V inhibitor SureCN5735477 f... 1 1
Tyrosine-protein kinase ABL1 inhibitor N-(5-bromopyridin-2-yl)... 1 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00408501 CHEMBL213641 Bioactive 3-[6-[3-(dimethylamino)pyrrolidin-1-yl]pyridin-3-yl]-7-phenoxychromen-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42686 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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