CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11341
Family Name Prostaglandin D2 receptor 2 ligand SureCN317401 family
No. of Seeds 3 No. of Other Members 8
Family Centroid CFAMM00408511 Functional Category Bioactive
Superfamily Prostaglandin D2 receptor 2 and Prostaglandin G/H synthase 1 Binder Superfamily
Class Class 926

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 4 171
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Histamine H1 receptor Ligand (s)-(+)-dimethindene Maleate Family 6 12
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodi... 1 4
Proteinase-activated receptor 1 Ligand SCH-530348 Family 20 215
Thromboxane A2 receptor Ligand Ramatroban Family 13 49
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Setipiprant family 5 118
5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 6 17
Prostaglandin E synthase Inhibitor L-655240 Family 3 46
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 19
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 8-(3... 4 22
Adenosine receptor A1 and Adenosine receptor A2a Ligand FK-838... 4 19
Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 3 11
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Trypsin Inhibitor 1-benzyl-1h-indole-5-carboxamidine Family 4 3
Cholinesterase Inhibitor 9-[9-(beta-carboline-9-yl)nonyl]-beta... 7 7
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 2 4
Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... 2 2
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Metabotropic glutamate receptor 5 Ligand 5-(2-methylquinolin-7... 4 3
Metabotropic glutamate receptor 5 Ligand 7-m-tolyl-1,6-naphthy... 4 2
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 10 7
Choline kinase alpha Inhibitor Bisquinolinium Derivative Family 2 1 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 2
Melanin-concentrating hormone receptor 1 ligand AGN-PC-09M6QF ... 3 0
Sigma non-opioid intracellular receptor 1 ligand SureCN7434677... 1 0
Prostaglandin D2 receptor 2 ligand 2-[5-fluoro-2-methyl-3-[(4-... 3 5
Integrase inhibitor (Z)-4-[5-chloro-1-[(4-fluorophenyl)methyl]... 3 9
Egl nine homolog 1 inhibitor 1'-[(3-methylpyridin-2-yl)methyl]... 6 4
Prostaglandin D2 receptor 2 and Prostaglandin G/H synthase 1 l... 3 17
Prostaglandin D2 receptor 2 and Cytochrome P450 2C19 ligand 2-... 6 13
Alpha-1A adrenergic receptor and D(2) dopamine receptor ligand... 1 0
Prostaglandin D2 receptor 2 ligand 2-[3-[(E)-2-cyano-3-(N-meth... 9 9
Aldo-keto reductase family 1 member B10 and Aldose reductase i... 5 0
methyl 11-cyclohexyl-1,2,3,3a,6,7-hexahydro-[1,4]diazepino[3,2... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00408514 CHEMBL213854 Bioactive SureCN316998
CFAMM00408511 CHEMBL214350 Bioactive SureCN317401
CFAMM00408517 CHEMBL214304 Bioactive SureCN317913

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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