CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11348
Family Name Sodium-dependent serotonin transporter and Sodium-dependent noradrenaline transporter inhibitor SureCN5450614 family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00077110 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 Inhibitor 1-benzyl-4-(2,4-dichlorophenyl)pyrrolidin-3-amine Superfamily
Class Class 48

Cousin Family NamesSeedsMembers
Serotonin re-uptake inhibitor tetralin derivative Sertraline f... 12 118
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82
Noradrenergic re-uptake Inhibitor Maprotiline Family 6 33
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21... 16 89
5-hydroxytryptamine receptor 2C Ligand Lorcaserin Family 8 38
Substance-P receptor Ligand Vestipitant Family 14 137
Zicronapine family 43 62
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 6 7
Adenosine receptor A3 and Glutamate receptor ionotropic, NMDA ... 4 30
Dipeptidyl peptidase 4 Inhibitor 2-(2-chlorophenyl)-2-morpholi... 2 34
Dipeptidyl peptidase 4 Inhibitor N4-(4-chlorobenzyl)-2,4-diami... 10 22
D(2) dopamine receptor and D(3) dopamine receptor Ligand ST-19... 5 27
Dipeptidyl peptidase 4 Inhibitor 1-benzyl-4-(2,4-dichloropheny... 2 10
Calcium-activated potassium channel subunit alpha-1 Ligand N-m... 2 10
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 17 9
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 1
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Sigma non-opioid intracellular receptor 1 ligand NCI60_038428 ... 5 9
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 4 13
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 7 9
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 2 0
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 18 4
Sigma non-opioid intracellular receptor 1 ligand 1-[2-(3,4-dic... 8 4
Transporter and Sodium-dependent dopamine transporter inhibito... 3 0
Transporter and Sodium-dependent serotonin transporter inhibit... 4 8
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 4
Substance-P receptor ligand AGN-PC-03NGZZ family 1 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 12
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 1
Substance-P receptor ligand (2R,3R)-2-benzhydryl-N-(2-iodophen... 2 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 5
Sodium-dependent noradrenaline transporter and Sodium-dependen... 3 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
Sigma non-opioid intracellular receptor 1 ligand NCI60_039912 ... 2 0
Sigma non-opioid intracellular receptor 1 and 3-beta-hydroxyst... 1 1
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 2 6
Melanin-concentrating hormone receptor 1 and Potassium voltage... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand (1R,5R)... 4 9
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 1
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 1
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[(3,4-dichlo... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand 2-[2-[(... 1 0
Prostaglandin E synthase inhibitor AGN-PC-09QMEJ family 2 0
Histamine H3 receptor ligand (2S)-N-[(3,4-dichlorophenyl)methy... 2 2
Melanocortin receptor 4 ligand 1-[3-[2-(4-tert-butylphenyl)phe... 1 3
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 10
Cannabinoid receptor 1 ligand AGN-PC-078YV8 family 1 2
Nociceptin receptor and Mu-type opioid receptor ligand (NE)-N-... 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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