CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11351
Family Name Melanin-concentrating hormone receptor 1 and Melanin-concentrating hormone receptor 1 ligand AGN-PC-03J6RH family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00244233 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and Beta-secretase 1 Binder Superfamily
Class Class 877

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 12 Inhibitor VX-702 Family 3 49
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Cannabinoid receptor 1 Ligand AZD2207 Family 18 48
Aurora kinase B and Aurora kinase A Inhibitor PF-03814735 Family 2 12
JAK Inhibitor Momelotinib Family 33 83
Neuropeptide Y receptor type 5 Ligand Npy5ra-972 Family 6 29
Lethal factor Inhibitor GM6001 Family 50 435
XL-888 family 16 85
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Telomerase reverse transcriptase Inhibitor HOE-33258 Family 10 33
Histamine H3 receptor Ligand 2-(4-isopropyl-piperazin-1-yl)-qu... 17 29
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
D(2) dopamine receptor and D(3) dopamine receptor Ligand A-706... 4 20
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Adenosine receptor A3 Ligand 1-(2-(diethylamino)quinazolin-4-y... 2 9
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2,6... 22 18
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 1 3
Epidermal growth factor receptor ligand AGN-PC-07Q1HU family 4 17
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 14 8
Prothrombin and Cationic trypsin inhibitor tert-butyl N-[(2R)-... 4 3
Melanin-concentrating hormone receptor 1 and Potassium voltage... 8 27
Melanin-concentrating hormone receptor 1 ligand AGN-PC-088XRP ... 2 10
Cathepsin K and Potassium voltage-gated channel subfamily H me... 4 7
5-hydroxytryptamine receptor 1A ligand AGN-PC-03ZB72 family 10 8
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 19
Melanin-concentrating hormone receptor 1 ligand AGN-PC-09M6QF ... 3 0
Mitogen-activated protein kinase 1 and Cytochrome P450 3A4 inh... 1 0
Adenosine receptor A2a ligand AGN-PC-077RWY family 4 5
Glucosylceramidase and Alpha-galactosidase A inhibitor AC1NNEG... 4 5
5-hydroxytryptamine receptor 1A ligand 2-[4-(quinolin-2-ylmeth... 2 91
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 1
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QKOM family 5 8
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
Beta-secretase 1 inhibitor 3-[2-amino-6-(2-methylphenyl)quinol... 5 2
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 18 5
Coagulation factor X inhibitor SureCN8289965 family 4 5
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
5-hydroxytryptamine receptor 3A ligand 3-methyl-N-[7-[[3-methy... 2 0
Substance-P receptor ligand 2-[3,5-bis(trifluoromethyl)phenyl]... 3 1
Translocator protein inhibitor N-butan-2-yl-4-(2-chlorophenyl)... 14 12
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(4-quinolin-2-ylpi... 1 0
Substance-P receptor ligand Netupitant family 5 2
Microsomal triglyceride transfer protein large subunit inhibit... 13 0
Melanin-concentrating hormone receptor 1 ligand SureCN4261878 ... 4 7
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 2
Succinate receptor 1 ligand N-[[4-(3-methylphenyl)phenyl]methy... 2 14
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 1
Melanin-concentrating hormone receptor 1 ligand SureCN6198980 ... 13 0
Transient receptor potential cation channel subfamily V member... 57 4
Transient receptor potential cation channel subfamily V member... 2 0
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 2 0
Dipeptidyl peptidase 4 inhibitor (4R,5R)-5-amino-1-[6-(3-methy... 2 5
Beta-secretase 1 inhibitor N-[(2S,3R)-3-amino-4-fluoro-1-pheny... 4 17
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor 6-... 1 0
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 2
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor (3R)-... 4 12
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... 2 14
C-X-C chemokine receptor type 3 ligand 1-[3-[[(1R,5S)-3-[[7-(t... 3 1
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 7 2
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-077RDJ family 15 1
Melanin-concentrating hormone receptor 1 ligand SureCN3832854 ... 3 2
Mast/stem cell growth factor receptor Kit and Tyrosine-protein... 4 1
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0
Melanin-concentrating hormone receptor 1 ligand SureCN3834858 ... 2 1
P2X purinoceptor 7 inhibitor 2-(1-adamantyl)-N-[2-(3-hydroxypr... 2 2
Dihydrofolate reductase inhibitor N-(2,4-diamino-5-methylquina... 2 0
Kinesin-like protein KIF11 inhibitor 9-(trifluoromethyl)-1,2,4... 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26854 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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