CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11352
Family Name Prolyl endopeptidase and Seprase inhibitor [(2R)-1-[2-[(2,5-dichlorobenzoyl)amino]acetyl]pyrrolidin-2-yl]boronic acid family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00408658 Functional Category Bioactive
Superfamily Substance-K receptor and Substance-P receptor Ligand DNK-333 Superfamily
Class Class 496

Cousin Family NamesSeedsMembers
Amine oxidase [flavin-containing] A Inhibitor Moclobemide Family 5 255
DNA Binder Procarbazine Family 8 358
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Neutrophil elastase Inhibitor FK-706 Family 8 85
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Prolyl endopeptidase and Seprase inhibitor [(2R)-1-[2-[benzoyl... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00408659 CHEMBL2141296 Bioactive MLN2238
CFAMM00408658 CHEMBL386890 Bioactive [(2R)-1-[2-[(2,5-dichlorobenzoyl)amino]acetyl]pyrrolidin-2-yl]boronic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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