CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11356
Family Name Melanin-concentrating hormone receptor 1 and Melanin-concentrating hormone receptor 1 ligand SureCN5150713 family
No. of Seeds 9 No. of Other Members 3
Family Centroid CFAMM00408681 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and D(2) dopamine receptor Binder Superfamily
Class Class 1677

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 8 39
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 7
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEH3 family 3 16
C-C chemokine receptor type 3 ligand SureCN6705515 family 2 16
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2C lig... 2 2
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 7
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[3-... 4 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 5
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 2 1
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
Integrin alpha-4 inhibitor SureCN14558473 family 7 4
Integrin alpha-4 inhibitor SureCN14558471 family 16 2
Bifunctional epoxide hydrolase 2 and RAF proto-oncogene serine... 4 10
Bifunctional epoxide hydrolase 2 inhibitor 8-(2,6-difluorobenz... 4 1
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Acyl-CoA desaturase 1 inhibitor AGN-PC-077KJY family 5 4
Acyl-CoA desaturase 1 inhibitor AGN-PC-077KFD family 1 1
Leukotriene A-4 hydrolase inhibitor SureCN5313952 family 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00408677 CHEMBL214322 Bioactive AGN-PC-00DDUW
CFAMM00408682 CHEMBL215418 Bioactive AGN-PC-00BNJA
CFAMM00408681 CHEMBL216010 Bioactive SureCN5150713
CFAMM00408685 CHEMBL214280 Bioactive AGN-PC-00D8VJ
CFAMM00408678 CHEMBL216192 Bioactive AGN-PC-004ZPR
CFAMM00408684 CHEMBL386247 Bioactive AGN-PC-00CDG8

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

22854 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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