CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11373
Family Name Sigma non-opioid intracellular receptor 1 ligand 1-[(3-nitrophenyl)methyl]-4-(3-phenylpropyl)piperazine family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00408799 Functional Category Bioactive
Superfamily Nitric oxide synthase, brain Inhibitor N*1*-(5-methyl-2-nitro-phenyl)-butane-1,4-diamine Superfamily
Class Class 2752

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
Vasopressin-neurophysin 2-copeptin Inhibitor Niravoline Family 7 45
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
Alpha-2A adrenergic receptor Ligand 7-nitro-1,2,3,4-tetrahydro... 6 31
Amyloid beta A4 protein Inhibitor 1,6-bis(4'-nitrophenyl)-hexa... 3 60
Histamine H3 receptor Ligand (r)-1-(4-nitrophenethyl)-2-methyl... 16 38
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
Nitric oxide synthase, brain Inhibitor N*1*-(5-methyl-2-nitro-... 1 19
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 18
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 31
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 7 27
5-hydroxytryptamine receptor 2A ligand AGN-PC-075LXD family 4 4
Sigma non-opioid intracellular receptor 1 ligand 2-(2-nitrophe... 2 5
Sigma non-opioid intracellular receptor 1 ligand 1-[4-[1-adama... 4 23
5-hydroxytryptamine receptor 7 ligand 1-[2-(4-nitrophenyl)phen... 1 0
Mu-type opioid receptor ligand CHEMBL2310836 family 4 4
Kappa-type opioid receptor ligand 1-[4-acetyl-2-[[(3S)-3-hydro... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 0
Nitric oxide synthase, brain and Nitric oxide synthase, induci... 1 2
Progesterone receptor and Androgen receptor ligand SureCN89245... 1 4
C-X-C chemokine receptor type 3 ligand [(1S,5R)-6,6-dimethyl-4... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00408799 CHEMBL272050 Bioactive 1-[(3-nitrophenyl)methyl]-4-(3-phenylpropyl)piperazine
CFAMM00408798 CHEMBL272819 Bioactive 1-[(2-nitrophenyl)methyl]-4-(3-phenylpropyl)piperazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24631 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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