CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11378
Family Name Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl]-3-[(2-chlorophenyl)methyl]-5-methyl-4-oxoimidazo[4,5-c]quinoline-7-carboxylic acid;hydrochloride family
No. of Seeds 7 No. of Other Members 15
Family Centroid CFAMM00408826 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and 5-hydroxytryptamine receptor 4 Binder Superfamily
Class Class 1060

Cousin Family NamesSeedsMembers
Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
Eluxadoline family 4 85
DNA (cytosine-5)-methyltransferase 3B Inhibitor NSC-57893 Family 3 8
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor Su... 16 5
Cellular tumor antigen p53 inhibitor CHEMBL1418224 family 1 62
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Dihydrofolate reductase inhibitor 2-[[4-carboxy-4-[[4-[(2,4-di... 3 1
Dihydrofolate reductase inhibitor AGN-PC-075RRH family 2 3
Bile acid receptor ligand 4-[[(2S)-2-[2-(4-chlorophenyl)-5,6-d... 4 12
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 8
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 1 0
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 3 4
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 7 12
Coagulation factor X inhibitor SureCN8289965 family 4 5
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 29
Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl... 2 0
Prostaglandin E synthase inhibitor 2-(2-chloro-6-fluorophenyl)... 9 1
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 3 6
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 1 1
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00408825 CHEMBL2147074 Bioactive 2-[2-[(3R)-3-aminopiperidin-1-yl]-3-[(2-chlorophenyl)methyl]-5-methyl-4-oxoimidazo[4,5-c]quinolin-7-yl]acetic acid;hydrochloride
CFAMM00408823 CHEMBL2147083 Bioactive 2-[2-[(3R)-3-aminopiperidin-1-yl]-3-[(2-chlorophenyl)methyl]-5-methyl-4-oxoimidazo[4,5-c]quinolin-8-yl]acetic acid;hydrochloride
CFAMM00408829 CHEMBL2147056 Bioactive 2-[(3R)-3-aminopiperidin-1-yl]-3-[(5-fluoro-2-methylphenyl)methyl]-5-methyl-4-oxoimidazo[4,5-c]quinoline-7-carboxylic acid;hydrochloride
CFAMM00408822 CHEMBL2147082 Bioactive 2-[(3R)-3-aminopiperidin-1-yl]-3-[(2-chlorophenyl)methyl]-5-methyl-4-oxoimidazo[4,5-c]quinoline-8-carboxylic acid;hydrochloride
CFAMM00408815 CHEMBL2147069 Bioactive 2-[(3R)-3-aminopiperidin-1-yl]-3-[(2-chloro-5-fluorophenyl)methyl]-5-methyl-4-oxoimidazo[4,5-c]quinoline-8-carboxylic acid;hydrochloride
CFAMM00408828 CHEMBL2147070 Bioactive 2-[(3R)-3-aminopiperidin-1-yl]-3-[(2-chloro-5-fluorophenyl)methyl]-5-methyl-4-oxoimidazo[4,5-c]quinoline-7-carboxylic acid;hydrochloride
CFAMM00408826 CHEMBL2147073 Bioactive 2-[(3R)-3-aminopiperidin-1-yl]-3-[(2-chlorophenyl)methyl]-5-methyl-4-oxoimidazo[4,5-c]quinoline-7-carboxylic acid;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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