CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11379
Family Name Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl]-3-[(2-chlorophenyl)methyl]-N,N,5-trimethyl-4-oxoimidazo[4,5-c]quinoline-7-carboxamide;hydrochloride family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00408832 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and 5-hydroxytryptamine receptor 4 Binder Superfamily
Class Class 1060

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Prothrombin Inhibitor Dabigatran Family 7 182
Dipeptidyl peptidase 4 Inhibitor Linagliptin Family 10 81
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
PHA848125 family 13 138
JAK Inhibitor Momelotinib Family 33 83
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Poly [ADP-ribose] polymerase 1 inhibitor 2-(3-chlorophenyl)-1H... 4 38
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-07ZE3... 6 1
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor Su... 16 5
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-09M4U... 4 5
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-09M45... 8 1
Cell division cycle 7-related protein kinase and Cyclin-depend... 2 9
Cell division cycle 7-related protein kinase inhibitor pyrrolo... 4 10
Cellular tumor antigen p53 inhibitor CHEMBL1418224 family 1 62
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1801305 ... 2 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 8
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 1 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 7 12
Coagulation factor X inhibitor SureCN8289965 family 4 5
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
Prostaglandin E synthase and Cytochrome P450 2C9 inhibitor 7-b... 1 7
Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl... 7 15
Prostaglandin E synthase inhibitor 2-(2-chloro-6-fluorophenyl)... 9 1
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... 2 14
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 4 3
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Melanin-concentrating hormone receptor 1 ligand SureCN3834858 ... 2 1
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-07B2Q... 6 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00408832 CHEMBL2147071 Bioactive 2-[(3R)-3-aminopiperidin-1-yl]-3-[(2-chlorophenyl)methyl]-N,N,5-trimethyl-4-oxoimidazo[4,5-c]quinoline-7-carboxamide;hydrochloride
CFAMM00408831 CHEMBL2147072 Bioactive 2-[(3R)-3-aminopiperidin-1-yl]-3-[(2-chlorophenyl)methyl]-5-methyl-4-oxoimidazo[4,5-c]quinoline-7-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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