CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11390
Family Name Serine/threonine-protein kinase pim-1 inhibitor (2Z)-6-methoxy-7-(piperazin-1-ylmethyl)-2-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylidene)-1-benzofuran-3-one family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00409079 Functional Category Bioactive with Natural Product
Superfamily Serine/threonine-protein kinase mTOR and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Binder Superfamily 2
Class Class 1256

Cousin Family NamesSeedsMembers
MO15-related protein kinase Pfmrk Inhibitor WR-289010 Family 2 506
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 20 28
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 391
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 9 3
Acetylcholinesterase and Butyrylcholinesterase inhibitor [3-[[... 3 68
Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N... 8 10
Glycylpeptide N-tetradecanoyltransferase 2 and Glycylpeptide N... 4 0
Melanin-concentrating hormone receptor 1 ligand 3-[6-[3-(dimet... 1 13
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 6 159
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 1 0
Histamine H1 receptor ligand 2-(3-hydroxy-6-oxoxanthen-9-yl)-5... 3 10
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Tyrosine-protein kinase ABL1 inhibitor N-(5-bromopyridin-2-yl)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00409079 CHEMBL2147767 Bioactive (2Z)-6-methoxy-7-(piperazin-1-ylmethyl)-2-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylidene)-1-benzofuran-3-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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