CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11402
Family Name Bone morphogenetic protein 1 inhibitor benzyl N-[(4R)-4-[1,3-benzodioxol-5-ylmethyl-(4-methoxyphenyl)sulfonylamino]-5-(hydroxyamino)-5-oxopentyl]carbamate family
No. of Seeds 6 No. of Other Members 25
Family Centroid CFAMM00409141 Functional Category Bioactive
Superfamily Bone morphogenetic protein 1 and Neutrophil collagenase Binder Superfamily
Class Class 954

Cousin Family NamesSeedsMembers
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 13
Cathepsin K inhibitor SureCN6578603 family 1 3
Pol polyprotein inhibitor benzyl (2S)-2-[[[(2S)-3-[cyclopentyl... 2 6
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Neutrophil collagenase and Stromelysin-1 inhibitor AGN-PC-075O... 14 27
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
ATP-dependent DNA helicase Q1 and Beta-lactamase inhibitor SMR... 1 2
Matrix metalloproteinase-15 and Matrix metalloproteinase-16 in... 1 0
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Macrophage metalloelastase and 72 kDa type IV collagenase inhi... 7 4
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 3 2
Bone morphogenetic protein 1 inhibitor 9H-fluoren-9-ylmethyl N... 1 24
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 0
Melanocortin receptor 4 ligand [(3R,4S)-4-(4-chlorophenyl)-1-p... 5 8
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 12 3
Bone morphogenetic protein 1 inhibitor (2R)-2-[1,3-benzodioxol... 1 6
Bone morphogenetic protein 1 inhibitor (2R)-2-[1,3-benzodioxol... 2 1
Motilin receptor ligand N-[1-[(1-amino-1-oxo-4-phenylbutan-2-y... 4 3
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R)-3-(1,3-b... 4 2
Coagulation factor X and Prothrombin inhibitor (3S)-N-(1,3-ben... 1 1
Bone morphogenetic protein 1 inhibitor (2R)-2-[1,3-benzodioxol... 2 0


External ID

Functional Category

Molecule Name

CFAMM00409141 CHEMBL21486 Bioactive benzyl N-[(4R)-4-[1,3-benzodioxol-5-ylmethyl-(4-methoxyphenyl)sulfonylamino]-5-(hydroxyamino)-5-oxopentyl]carbamate
CFAMM00409137 CHEMBL65208 Bioactive methyl 4-[[(2R)-2-[1,3-benzodioxol-5-ylmethyl-(4-methoxyphenyl)sulfonylamino]-3-(hydroxyamino)-3-oxopropyl]carbamoyl]benzoate
CFAMM00409159 CHEMBL279023 Bioactive (2-chlorophenyl)methyl N-[(4R)-4-[1,3-benzodioxol-5-ylmethyl-(4-methoxyphenyl)sulfonylamino]-5-(hydroxyamino)-5-oxopentyl]carbamate
CFAMM00409145 CHEMBL432532 Bioactive (2R)-5-(4-acetylpiperazin-1-yl)-2-[1,3-benzodioxol-5-ylmethyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-5-oxopentanamide
CFAMM00409133 CHEMBL282484 Bioactive (2-chlorophenyl)methyl N-[(4R)-2-amino-4-[1,3-benzodioxol-5-ylmethyl-(4-methoxyphenyl)sulfonylamino]-5-(hydroxyamino)-3,5-dioxopentyl]carbamate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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