CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11405
Family Name Melanin-concentrating hormone receptor 1 ligand SureCN4261878 family
No. of Seeds 4 No. of Other Members 7
Family Centroid CFAMM00409190 Functional Category Bioactive
Superfamily Kappa-type opioid receptor and Mu-type opioid receptor Ligand 2-(2-methylquinolin-4-ylamino)-n-phenylacetamide Superfamily
Class Class 1105

Cousin Family NamesSeedsMembers
Glutamate dehydrogenase inhibitor quinoline derivative Chloroq... 7 189
Acetylcholinesterase Inhibitor Tacrine Family 12 515
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
Neuromedin-K receptor Ligand SB222200 Family 17 235
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
D(3) dopamine receptor Ligand SB-277011 Family 13 178
D(4) dopamine receptor Ligand SPI-376 Family 7 84
Neuropeptide Y receptor type 5 Ligand Npy5ra-972 Family 6 29
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
Lethal factor Inhibitor N,n'-bis(4-amino-2-methylquinolin-6-yl... 2 11
5-hydroxytryptamine receptor 2A Ligand 8-chloro-1,2,3,4-tetrah... 5 4
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 43 17
Poly [ADP-ribose] polymerase 1 Inhibitor 2-ethylquinoline-8-ca... 3 4
Transient receptor potential cation channel subfamily V member... 6 23
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Metabotropic glutamate receptor 5 Ligand 1-(3-(2-methylquinoli... 2 12
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Substance-P receptor ligand AGN-PC-01ZIXQ family 13 42
Epidermal growth factor receptor ligand AGN-PC-07Q1HU family 4 17
Corticotropin-releasing factor receptor 1 ligand N-(cyclopropy... 2 2
Cannabinoid receptor 1 ligand AGN-PC-04YSUM family 7 6
Melanin-concentrating hormone receptor 1 and Potassium voltage... 8 27
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 13 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-072CVE ... 4 4
Melanin-concentrating hormone receptor 1 ligand AGN-PC-09M6QF ... 3 0
Cellular tumor antigen p53 and Ferritin light chain inhibitor ... 1 2
Translocator protein inhibitor (2E)-N-(4-chlorophenyl)-N-methy... 2 13
Glucosylceramidase and Alpha-galactosidase A inhibitor AC1NNEG... 4 5
Melatonin receptor type 1A and Melatonin receptor type 1C liga... 2 5
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 1
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QKOM family 5 8
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Epidermal growth factor receptor and Receptor tyrosine-protein... 3 0
Melanin-concentrating hormone receptor 2 and Sodium-dependent ... 2 1
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 2 9
Melanin-concentrating hormone receptor 1 and 5-hydroxytryptami... 1 1
Translocator protein inhibitor N-butan-2-yl-4-(2-chlorophenyl)... 14 12
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 2
Melanin-concentrating hormone receptor 1 ligand SureCN6198980 ... 13 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 8 6
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Acetylcholinesterase inhibitor N-[6-[4-[(6-chloro-1,2,3,4-tetr... 9 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2
Capsid scaffolding protein inhibitor AC1O583J family 5 1
Telomerase reverse transcriptase inhibitor N-[9-(4-aminoanilin... 1 11
Melanin-concentrating hormone receptor 1 ligand SureCN6200892 ... 1 0
Plasmepsin-2 and Cathepsin D inhibitor N'-(3,4-dimethylacridin... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0
Gamma-aminobutyric acid receptor subunit beta-3 and Gamma-amin... 2 5
Dihydrofolate reductase inhibitor N-(2,4-diamino-5-methylquina... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00409188 CHEMBL217614 Bioactive SureCN6202826
CFAMM00409192 CHEMBL214888 Bioactive SureCN6201933
CFAMM00409182 CHEMBL385957 Bioactive SureCN6202988
CFAMM00409190 CHEMBL214985 Bioactive SureCN4261878

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

44434 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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