CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11409
Family Name Cathepsin S and Cathepsin K inhibitor SureCN3018173 family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00409229 Functional Category Bioactive
Superfamily Emricasan Superfamily
Class Class 1297

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Substance-K receptor Ligand MEN-14933 Family 13 154
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 11 13
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Renin Inhibitor Ro-66-1168 Family 10 30
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
Cathepsin K inhibitor N-[(2S)-1-(4-methoxyanilino)propan-2-yl]... 11 10
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEH3 family 3 16
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-087THW family 1 0
Renin inhibitor 6-[[(2R)-1-[4-[3-[(2-methoxyphenyl)methoxy]pro... 3 1
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 7 10
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 4 0
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 4 3
Cathepsin S and Cathepsin K inhibitor SureCN3011598 family 1 11
Bifunctional epoxide hydrolase 2 inhibitor 8-(2-ethylbutanoyl)... 11 0
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 20 23
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-00RZQT family 3 4
Hormone-sensitive lipase inhibitor [4-[(4-tert-butylcyclohexan... 2 1
fMet-Leu-Phe receptor ligand 2-[[(2S)-2-[[(2S)-2-[(4-methoxyph... 1 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor [(... 2 3
Histone deacetylase 8 and Histone deacetylase 6 inhibitor (3S)... 4 16
Melanocortin receptor 4 ligand [4-[2-[(1S)-1-amino-3-methylbut... 1 0
Sodium channel protein type 9 subunit alpha ligand SureCN12900... 9 8
Matrix metalloproteinase-9 and Metalloproteinase inhibitor 3 i... 1 3
Elongation of very long chain fatty acids protein 6 inhibitor ... 2 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00409229 CHEMBL214982 Bioactive SureCN3018173

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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