CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11423
Family Name Aurora kinase A and Cyclin-dependent kinase 4 inhibitor 2-[3-[(7-cyclohexylpyrrolo[2,3-d]pyrimidin-2-yl)amino]phenyl]acetic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00095060 Functional Category Bioactive
Superfamily Integrin alpha-4 Inhibitor CDP323 Superfamily
Class Class 898

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Aurora kinase A Inhibitor MLN8054 Family 2 5
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[6-m... 13 12
Dihydrofolate reductase inhibitor 2-[[4-carboxy-4-[[4-[(2,4-di... 3 1
Dihydrofolate reductase inhibitor AGN-PC-075RRH family 2 3
Carboxypeptidase B2 and Carboxypeptidase B inhibitor 3-(6-amin... 5 10
Prostaglandin D2 receptor 2 ligand 2-[(8R)-8-[(4-fluorophenyl)... 3 15
Prostaglandin D2 receptor 2 ligand SureCN2215286 family 7 5
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
Aurora kinase A inhibitor Bisanilinopyrimidine, 6i family 1 0
Aurora kinase A inhibitor Bisanilinopyrimidine, 6j family 2 1
Tyrosine-protein kinase JAK2 inhibitor 4-[[8-(1-propan-2-ylpyr... 5 6
Prostaglandin D2 receptor 2 and Cholecystokinin receptor type ... 3 4
Type-1 angiotensin II receptor ligand 2-ethyl-4-[[4-[2-(2H-tet... 2 0
Diacylglycerol O-acyltransferase 1 inhibitor 2-[4-[4-(4-amino-... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27398 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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