CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1143
Family Name Neutrophil elastase inhibitor 2-[3-(benzylsulfamoylamino)-2-oxo-6-phenylpyridin-1-yl]-N-(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)acetamide family
No. of Seeds 5 No. of Other Members 27
Family Centroid CFAMM00319985 Functional Category Bioactive
Superfamily Neutrophil elastase and C-C chemokine receptor type 5 Binder Superfamily
Class Class 3296

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor 3-benzylamino-5-ethyl-6-methyl... 2 24
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Neutrophil elastase Inhibitor FK-706 Family 8 85
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 3 26
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Substance-P receptor ligand AGN-PC-00FJ8P family 6 10
Neutrophil elastase and Chymotrypsin-C inhibitor benzyl N-[6-(... 3 6
Prothrombin and Trypsin-1 inhibitor AGN-PC-073KRV family 3 4
Prothrombin and Trypsin-1 inhibitor N-[[2-(2-aminoethyl)-5-chl... 3 2
Neutrophil elastase inhibitor SureCN7423499 family 5 1
Cannabinoid receptor 2 ligand AGN-PC-087MPO family 7 21
B1 bradykinin receptor ligand N-[(1R)-6-[(dimethylamino)methyl... 7 6
B1 bradykinin receptor ligand N-[(4R)-1,1-dioxo-3,4-dihydro-2H... 1 0
B1 bradykinin receptor ligand N-[(4S)-1-ethyl-3,3-dimethylpipe... 10 4
Prothrombin inhibitor 2-[3-(benzylsulfonylamino)-6-methyl-2-ox... 2 3
Prothrombin inhibitor N-[[(5R,6R)-2-amino-6-methyl-1,4,5,6-tet... 3 2
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(4... 5 1
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-[(4-nitrobenz... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00319972 CHEMBL304354 Bioactive 2-[3-(benzenesulfonamido)-2-oxo-6-phenylpyridin-1-yl]-N-(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)acetamide
CFAMM00319978 CHEMBL111955 Bioactive SureCN5076881
CFAMM00319985 CHEMBL282694 Bioactive 2-[3-(benzylsulfamoylamino)-2-oxo-6-phenylpyridin-1-yl]-N-(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)acetamide
CFAMM00319954 CHEMBL431864 Bioactive 2-[3-(benzylsulfonylamino)-2-oxo-6-phenylpyridin-1-yl]-N-(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)acetamide
CFAMM00319974 CHEMBL113358 Bioactive 2-[3-(benzylcarbamoylamino)-2-oxo-6-phenylpyridin-1-yl]-N-(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27291 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543