CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11443
Family Name Cholesteryl ester transfer protein inhibitor 1-[(1S)-1-(5-chloropyridin-2-yl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-3-(3,3,3-trifluoropropyl)urea family
No. of Seeds 11 No. of Other Members 8
Family Centroid CFAMM00409426 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 2A and Beta-lactamase Binder Superfamily
Class Class 3170

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf inhibitor diaryl urea an... 12 93
Epidermal growth factor receptor and Receptor tyrosine-protein... 8 31
Reverse transcriptase/RNaseH inhibitor 1-[2-(6-chloro-3-ethoxy... 7 5
5-hydroxytryptamine receptor 2C and Cytochrome P450 1A2 ligand... 6 4
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 2 7
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 4 2
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 1 0
P2Y purinoceptor 1 inhibitor 1-(4-tert-butylphenyl)-3-[2-(2-pr... 4 14
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 4 4
Melanin-concentrating hormone receptor 1 ligand 3-[4-fluoro-3-... 1 1
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00409428 CHEMBL2152167 Bioactive 1-[(1S)-1-(5-chloropyridin-2-yl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-3-[(1R)-3,3-difluorocyclopentyl]urea
CFAMM00409427 CHEMBL2152183 Bioactive 1-[(1S)-1-(5-chloropyridin-2-yl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-3-(2,2,2-trifluoroethyl)urea
CFAMM00409433 CHEMBL2152168 Bioactive 1-[(1S)-1-(5-chloropyridin-2-yl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-3-[(1S)-3,3-difluorocyclopentyl]urea
CFAMM00409426 CHEMBL2152180 Bioactive 1-[(1S)-1-(5-chloropyridin-2-yl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-3-(3,3,3-trifluoropropyl)urea
CFAMM00409439 CHEMBL2152170 Bioactive 1-[(1S)-1-(5-chloropyridin-2-yl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-3-(3,3-difluorocyclobutyl)urea
CFAMM00409425 CHEMBL2152181 Bioactive 1-[(1S)-1-(5-chloropyridin-2-yl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-3-(2,2,3,3,3-pentafluoropropyl)urea
CFAMM00409431 CHEMBL2152169 Bioactive 1-[(1S)-1-(5-chloropyridin-2-yl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-3-(2,2-difluorocyclopropyl)urea
CFAMM00409437 CHEMBL2152179 Bioactive 1-[(1S)-1-(5-chloropyridin-2-yl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-3-propylurea
CFAMM00409430 CHEMBL2152165 Bioactive 1-[(1S)-1-(5-chloropyridin-2-yl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-3-cyclopentylurea
CFAMM00409429 CHEMBL2152166 Bioactive 1-[(1S)-1-(5-chloropyridin-2-yl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-3-(3,3-difluorocyclopentyl)urea
CFAMM00409442 CHEMBL2152175 Bioactive N-[(1S)-1-(5-chloropyridin-2-yl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-3,3,4,4-tetrafluoropyrrolidine-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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