CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11458
Family Name Histamine H1 receptor ligand 2-(3-hydroxy-6-oxoxanthen-9-yl)-5-[4-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl-methylamino]butylcarbamoyl]benzoic acid family
No. of Seeds 3 No. of Other Members 10
Family Centroid CFAMM00409515 Functional Category Bioactive with Natural Product
Superfamily Pol polyprotein and Histamine H1 receptor Binder Superfamily
Class Class 1612

Cousin Family NamesSeedsMembers
Aldo-keto reductase family 1 member B10 and Aldose reductase i... 4 13
Rho-associated protein kinase 2 and cGMP-dependent protein kin... 1 1
Melanin-concentrating hormone receptor 1 ligand 3-[6-[3-(dimet... 1 13
Serine/threonine-protein kinase pim-1 inhibitor (2Z)-6-methoxy... 1 5
Integrin beta-3 and Integrin alpha-V inhibitor SureCN5735477 f... 1 1
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 0


External ID

Functional Category

Molecule Name

CFAMM00409526 CHEMBL277850 Bioactive 2-(3-hydroxy-6-oxoxanthen-9-yl)-4-[8-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl-methylamino]octylcarbamoyl]benzoic acid
CFAMM00409515 CHEMBL21525 Bioactive 2-(3-hydroxy-6-oxoxanthen-9-yl)-5-[4-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl-methylamino]butylcarbamoyl]benzoic acid
CFAMM00409519 CHEMBL21721 Bioactive 2-(3-hydroxy-6-oxoxanthen-9-yl)-5-[8-[2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl-methylamino]octylcarbamoyl]benzoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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