CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11477
Family Name Mitogen-activated protein kinase 14 inhibitor Skepinone-L family
No. of Seeds 11 No. of Other Members 31
Family Centroid CFAMM00409629 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 Binder Superfamily 8
Class Class 2482

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand JT... 14 4
Histone deacetylase 2 Inhibitor N-(4-amino-3'-methoxybiphenyl-... 3 49
Transient receptor potential cation channel subfamily V member... 2 29
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 5
Mitogen-activated protein kinase 14 inhibitor N-[2,4-difluoro-... 4 1
Mitogen-activated protein kinase 14 inhibitor N-[2-fluoro-5-[(... 4 5
Mitogen-activated protein kinase 14 inhibitor N-[2-fluoro-5-[(... 1 11
Mitogen-activated protein kinase 14 inhibitor ethyl 3-(2,4-dif... 5 1
Mitogen-activated protein kinase 14 inhibitor N-[5-[[9-[[(4S)-... 2 0
Mitogen-activated protein kinase 14 inhibitor SureCN4222090 fa... 1 12


External ID

Functional Category

Molecule Name

CFAMM00409618 CHEMBL2316483 Bioactive N-[2-fluoro-5-[[9-(2-hydroxyethoxy)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulen-3-yl]amino]phenyl]benzamide
CFAMM00409624 CHEMBL2152941 Bioactive 3-(2,4-difluoroanilino)-9-(3-hydroxypropoxy)-5,6-dihydrodibenzo[3,1-[7]annulen-11-one
CFAMM00409617 CHEMBL2316488 Bioactive N-[4-fluoro-3-[[9-(2-hydroxyethoxy)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulen-3-yl]amino]phenyl]benzamide
CFAMM00409601 CHEMBL2152938 Bioactive 3-(2-aminoanilino)-9-[(2S)-2,3-dihydroxypropoxy]-5,6-dihydrodibenzo[3,1-[7]annulen-11-one
CFAMM00409623 CHEMBL2152960 Bioactive 8-(2,4-difluoroanilino)-3-[(2S)-2,3-dihydroxypropoxy]-5,6-dihydrodibenzo[3,1-b:3',1'-f][7]annulen-11-one
CFAMM00409625 CHEMBL2152940 Bioactive 3-(2,4-difluoroanilino)-9-(2-hydroxyethoxy)-5,6-dihydrodibenzo[3,1-[7]annulen-11-one
CFAMM00409631 CHEMBL2152946 Bioactive 3-(2,4-difluoroanilino)-9-[(2S)-2,3-dihydroxypropoxy]-5,6-dihydrodibenzo[3,1-[7]annulen-11-one
CFAMM00409630 CHEMBL2152947 Bioactive 3-(2,4-difluoroanilino)-9-[2-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethoxy]-5,6-dihydrodibenzo[3,1-[7]annulen-11-one
CFAMM00409629 CHEMBL2152944 Bioactive Skepinone-L
CFAMM00409620 CHEMBL2152948 Bioactive 3-(2,4-difluoroanilino)-9-[(3R)-3,4-dihydroxybutoxy]-5,6-dihydrodibenzo[3,1-[7]annulen-11-one
CFAMM00409612 CHEMBL2316486 Bioactive N-[5-[[9-[(2S)-2,3-dihydroxypropoxy]-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulen-3-yl]amino]-2-fluorophenyl]benzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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