CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11478
Family Name Mitogen-activated protein kinase 14 inhibitor N-[2,4-difluoro-5-[[9-(2-morpholin-4-ylethoxy)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulen-3-yl]amino]phenyl]benzamide family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00409644 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 Binder Superfamily 8
Class Class 2482

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand JT... 14 4
Histone deacetylase 2 Inhibitor N-(4-amino-3'-methoxybiphenyl-... 3 49
Kappa-type opioid receptor ligand AGN-PC-09M90I family 2 3
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 5
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Microsomal triglyceride transfer protein large subunit inhibit... 3 0
Mitogen-activated protein kinase 14 inhibitor Skepinone-L family 11 31
Mitogen-activated protein kinase 14 inhibitor N-[2-fluoro-5-[(... 4 5
Mitogen-activated protein kinase 14 inhibitor ethyl 3-(2,4-dif... 5 1
Mitogen-activated protein kinase 14 inhibitor N-[5-[[9-[[(4S)-... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00409640 CHEMBL2152950 Bioactive 3-(2,4-difluoroanilino)-9-(3-morpholin-4-ylpropoxy)-5,6-dihydrodibenzo[3,1-[7]annulen-11-one
CFAMM00409644 CHEMBL2316497 Bioactive N-[2,4-difluoro-5-[[9-(2-morpholin-4-ylethoxy)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulen-3-yl]amino]phenyl]benzamide
CFAMM00409643 CHEMBL2152949 Bioactive 3-(2,4-difluoroanilino)-9-(2-morpholin-4-ylethoxy)-5,6-dihydrodibenzo[3,1-[7]annulen-11-one
CFAMM00409641 CHEMBL2316485 Bioactive N-[2-fluoro-5-[[9-(2-morpholin-4-ylethoxy)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulen-3-yl]amino]phenyl]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26380 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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