CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11482
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 6-(dimethylamino)-N-(5-hydroxy-2-adamantyl)-2-propylsulfanylpyridine-3-carboxamide family
No. of Seeds 4 No. of Other Members 8
Family Centroid CFAMM00409655 Functional Category Bioactive
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 and Lethal(3)malignant brain tumor-like protein 1 Binder Superfamily
Class Class 1177

Cousin Family NamesSeedsMembers
Integrin beta-3 and Integrin alpha-V inhibitor SureCN547914 fa... 8 32
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-[(1... 2 5
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 2-cyc... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(3-fluor... 10 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00409665 CHEMBL2158470 Bioactive N-(5-hydroxy-2-adamantyl)-6-morpholin-4-yl-2-propylsulfanylpyridine-3-carboxamide
CFAMM00409660 CHEMBL2153191 Bioactive 2-[(3S)-1-[5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]piperidin-3-yl]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26380 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543