CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11492
Family Name Metabotropic glutamate receptor 5 ligand 5-methyl-N-(4-methyl-1,3-thiazol-2-yl)-1H-pyrrolo[2,3-c]pyridine-7-carboxamide family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00409731 Functional Category Bioactive
Superfamily Beta-lactamase and Neuropeptide Y receptor type 5 Binder Superfamily
Class Class 3430

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Reverse transcriptase Inhibitor Nevirapine Family 23 640
5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
Purine nucleoside phosphorylase Inhibitor BCX-34 Family 2 31
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 2 13
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 2 1
Receptor tyrosine-protein kinase erbB-2 ligand AGN-PC-07ZDR2 f... 7 33
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
Thyroid hormone receptor beta and Ferritin light chain ligand ... 3 10
Prothrombin inhibitor (3R,6S,8aS)-N-[5-(diaminomethylideneamin... 2 3
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
Metabotropic glutamate receptor 5 ligand SureCN3866791 family 2 10
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 2
MAP kinase-activated protein kinase 2 inhibitor 4-fluoro-N-[4-... 25 1
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Glycogen synthase kinase-3 beta inhibitor N-[2-[4-(ethylsulfon... 2 2
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
D(3) dopamine receptor and D(2) dopamine receptor ligand [4-[2... 5 5
D(3) dopamine receptor and D(2) dopamine receptor ligand [4-[2... 6 5
Metabotropic glutamate receptor 5 ligand 2-methyl-N-(6-methylp... 1 8
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 0
Serine/threonine-protein kinase Chk1 inhibitor 2-(1,3-dihydroi... 2 5
Serine/threonine-protein kinase Chk1 inhibitor 2-indazol-1-yl-... 4 5
Glucocorticoid receptor ligand 3-(1H-indol-5-yl)-2,2-dimethyl-... 2 7
MAP kinase-activated protein kinase 2 inhibitor 2-[(4,4-dimeth... 11 11
Tyrosine-protein kinase Lck inhibitor AGN-PC-03HL8Q family 4 0
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 5 0
Methionine aminopeptidase and Methionine aminopeptidase 1 inhi... 3 7
Methionine aminopeptidase and Methionine aminopeptidase 1 inhi... 11 2
Methionine aminopeptidase and Methionine aminopeptidase 1 inhi... 3 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
Glucokinase inhibitor AGN-PC-078XNA family 2 9
Tyrosyl-DNA phosphodiesterase 1 and ATP-dependent molecular ch... 1 0
Histamine H3 receptor ligand 3-[2-[2-(1H-imidazol-5-yl)ethylsu... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00409731 CHEMBL2153783 Bioactive 5-methyl-N-(4-methyl-1,3-thiazol-2-yl)-1H-pyrrolo[2,3-c]pyridine-7-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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