CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11496
Family Name Mu-type opioid receptor ligand 4-[(2S)-3-[[(2S)-1-(4-hydroxyphenyl)-3-[methyl-[(2S)-1-[(2S)-2-(methylaminomethyl)pyrrolidin-1-yl]-3-phenylpropan-2-yl]amino]propan-2-yl]-methylamino]-2-(methylamino)propyl]phenol family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00409755 Functional Category Bioactive
Superfamily Fibroblast growth factor receptor Ligand SU5403 Superfamily
Class Class 62

Cousin Family NamesSeedsMembers
Vasopressin V2 receptor ligand peptide analog Desmopressin family 111 1472
Beta adrenergic receptor ligand catecholamine group Isoprotere... 7 130
Alpha adrenergic receptor ligand catecholamine Phenylephrine F... 4 39
Beta-2 adrenergic receptor ligand catecholamine Salbutamol Family 10 90
Oxytocin receptor Ligand Oxytocin Family 30 182
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Glucan synthesis regulatory protein Inhibitor Caspofungin Family 17 71
Kappa-type opioid receptor Ligand Dezocine Family 36 46
Mu-type opioid receptor Ligand Alvimopan Family 32 325
Noradrenergic re-uptake Inhibitor Desvenalfaxine Succinate Family 2 4
Thymopentin family 20 133
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 6 40
Tryptase Inhibitor APC-366 Family 2 12
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Neuropeptide Y receptor type 1 Ligand Bibp 3226 Family 43 80
Vasopeptidase Inhibitor Sampatrilat Family 25 9
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 20 35
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 11
Proto-oncogene tyrosine-protein kinase Src Inhibitor Glu-pro-g... 8 4
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 23 9
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 31 5
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Mu-type opioid receptor and Nociceptin receptor Ligand Ac-ryyr... 60 11
C-X-C chemokine receptor type 4 Ligand Cyclo(-d-tyr-l-ala-l-ar... 25 23
Prothrombin Inhibitor Cyclotheonamide E5 Family 3 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 8
Genome polyprotein Inhibitor Acasp-glu-dif-ile-cha-cys-iqc-nle... 9 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 3 0
Sodium-dependent dopamine transporter Inhibitor Bip-tyr-thr-pr... 8 2
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 48 10
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
Angiotensin-converting enzyme and Neprilysin inhibitor (2S,5R)... 15 3
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 2 0
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4R)-4-(3-hydroxyp... 4 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 3 1
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00409755 CHEMBL215595 Bioactive 4-[(2S)-3-[[(2S)-1-(4-hydroxyphenyl)-3-[methyl-[(2S)-1-[(2S)-2-(methylaminomethyl)pyrrolidin-1-yl]-3-phenylpropan-2-yl]amino]propan-2-yl]-methylamino]-2-(methylamino)propyl]phenol
CFAMM00409753 CHEMBL215809 Bioactive 4-[(2S)-2-[[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-methylamino]-3-[methyl-[(2S)-1-[(2S)-2-(methylaminomethyl)pyrrolidin-1-yl]-3-phenylpropan-2-yl]amino]propyl]phenol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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