CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11498
Family Name Melanin-concentrating hormone receptor 1 ligand SureCN6198980 family
No. of Seeds 13 No. of Other Members 0
Family Centroid CFAMM00409766 Functional Category Bioactive
Superfamily Kappa-type opioid receptor and Mu-type opioid receptor Ligand 2-(2-methylquinolin-4-ylamino)-n-phenylacetamide Superfamily
Class Class 1105

Cousin Family NamesSeedsMembers
Acetylcholinesterase Inhibitor Tacrine Family 12 515
Neuromedin-K receptor Ligand SB222200 Family 17 235
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Glucagon receptor Ligand Dwlip-gcgrrx Family 5 26
Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
Neuropeptide Y receptor type 5 Ligand Npy5ra-972 Family 6 29
Lethal factor Inhibitor N,n'-bis(4-amino-2-methylquinolin-6-yl... 2 11
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 43 17
Poly [ADP-ribose] polymerase 1 Inhibitor 2-ethylquinoline-8-ca... 3 4
Protein kinase C theta type Inhibitor 4-(3h-indol-4-ylamino)-5... 2 2
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Urotensin-2 receptor Ligand Palosuran Family 4 4
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 10
Metabotropic glutamate receptor 5 Ligand 3-fluoro-5-(2-methylq... 3 2
Protein kinase C alpha type Inhibitor Dequalinium Analogue Family 1 10
Acetylcholinesterase and Cholinesterase Inhibitor Huprine-tacr... 62 27
Epidermal growth factor receptor ligand AGN-PC-07Q1HU family 4 17
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 11 20
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 13 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-09M6QF ... 3 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 1
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QKOM family 5 8
C-C chemokine receptor type 3 ligand 1-[(1R,2S)-2-[[3-[(4-fluo... 3 2
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 0
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 0
Melanin-concentrating hormone receptor 1 ligand SureCN4261878 ... 4 7
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 2
Cholinesterase and Acetylcholinesterase inhibitor [2,2-dimethy... 2 0
Telomerase reverse transcriptase inhibitor N-[9-(4-aminoanilin... 1 11
Melanin-concentrating hormone receptor 1 ligand SureCN6200892 ... 1 0
Plasmepsin-2 and Cathepsin D inhibitor N'-(3,4-dimethylacridin... 1 0
Gamma-aminobutyric acid receptor subunit beta-3 and Gamma-amin... 2 5
Dihydrofolate reductase inhibitor N-(2,4-diamino-5-methylquina... 2 0
Kinesin-like protein KIF11 inhibitor 9-(trifluoromethyl)-1,2,4... 4 1
Acetylcholinesterase inhibitor (9R)-11-amino-6,6,9-trimethyl-9... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00409769 CHEMBL386320 Bioactive SureCN6202827
CFAMM00409762 CHEMBL384765 Bioactive SureCN6202043
CFAMM00409768 CHEMBL216565 Bioactive SureCN6199363
CFAMM00409761 CHEMBL215649 Bioactive SureCN6203999
CFAMM00409767 CHEMBL216428 Bioactive SureCN6201704
CFAMM00409760 CHEMBL386727 Bioactive SureCN6199666
CFAMM00409766 CHEMBL216324 Bioactive SureCN6198980
CFAMM00409759 CHEMBL412831 Bioactive SureCN6223165
CFAMM00409765 CHEMBL87370 Bioactive SureCN6204654
CFAMM00409771 CHEMBL439358 Bioactive SureCN6204350
CFAMM00409764 CHEMBL385941 Bioactive SureCN6203179
CFAMM00409770 CHEMBL386284 Bioactive SureCN6204287
CFAMM00409763 CHEMBL384547 Bioactive SureCN6204521

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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