CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11509
Family Name Cholinesterase and Acetylcholinesterase inhibitor 3-[ethyl-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]amino]-N-(4-phenyl-1,3-thiazol-2-yl)propanamide family
No. of Seeds 6 No. of Other Members 9
Family Centroid CFAMM00250145 Functional Category Bioactive
Superfamily Prelamin-A/C and Inositol monophosphatase 1 Binder Superfamily 8
Class Class 3854

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-me... 2 45
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
C-C chemokine receptor type 4 Ligand N-(naphthalen-1-yl)-4-neo... 5 78
C-C chemokine receptor type 4 Ligand N-(4-tert-butylthiazol-2-... 3 9
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 4 3
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(4-acet... 4 12
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 2 5
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 1 inhibi... 2 0
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-phenyl-1,3-t... 3 4
Cathepsin K and Cathepsin L1 inhibitor (2R)-N-(cyanomethyl)-4-... 2 1
Vascular endothelial growth factor receptor 2 ligand N-(1,3-Th... 4 4
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(1,4-di... 3 3
Glucocorticoid receptor ligand 3-(1H-indol-5-yl)-2,2-dimethyl-... 2 7
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 10
Neuropeptide Y receptor type 5 ligand 2-(dimethylamino)-1-[4-[... 10 5
Neuropeptide Y receptor type 5 ligand 1-[4-[[(9-fluoro-5,6-dih... 11 0
Integrin beta-3 and Integrin alpha-IIb inhibitor 4-[[4-(4-carb... 4 2
Membrane primary amine oxidase inhibitor N-[4-[2-[4-(diaminome... 5 0
Methionine aminopeptidase 1 inhibitor N-[5-[2-oxo-2-[4-(2-pyri... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00409820 CHEMBL2158112 Bioactive N'-(4-phenyl-1,3-thiazol-2-yl)-N-[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]butanediamide
CFAMM00409830 CHEMBL2158123 Bioactive N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-3-[ethyl-[3-(1,2,3,4-tetrahydroacridin-9-ylamino)propyl]amino]propanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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