CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11537
Family Name 5-hydroxytryptamine receptor 7 and D(2) dopamine receptor ligand 5-chloro-N-[(3R)-1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide family
No. of Seeds 5 No. of Other Members 17
Family Centroid CFAMM00410246 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 7 and D(2) dopamine receptor Binder Superfamily
Class Class 4727

Cousin Family NamesSeedsMembers
Leukotriene A-4 hydrolase inhibitor SureCN13809114 family 2 7
5-hydroxytryptamine receptor 7 ligand 5-chloro-N-[1-[2-(2-meth... 2 5
5-hydroxytryptamine receptor 7 ligand 4-fluoro-N-[1-[2-(2-phen... 6 3
Alpha-1A adrenergic receptor and D(2) dopamine receptor ligand... 5 20
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 1
5-hydroxytryptamine receptor 7 and D(2) dopamine receptor liga... 1 0
Presenilin-1 and Presenilin-2 inhibitor AGN-PC-075BQZ family 1 2


External ID

Functional Category

Molecule Name

CFAMM00410244 CHEMBL2159487 Bioactive 5-chloro-N-[(3R)-1-[2-(2-propan-2-ylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
CFAMM00410257 CHEMBL2159491 Bioactive 5-chloro-N-[(3S)-1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
CFAMM00410246 CHEMBL2159488 Bioactive 5-chloro-N-[(3R)-1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
CFAMM00410239 CHEMBL2159321 Bioactive 5-chloro-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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