CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11538
Family Name 5-hydroxytryptamine receptor 7 ligand 5-chloro-N-[1-[2-(2-methylsulfanylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00410262 Functional Category Bioactive
Superfamily Beta-lactamase and 5-hydroxytryptamine receptor 7 Binder Superfamily 2
Class Class 4852

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 7 and D(2) dopamine receptor liga... 5 17
5-hydroxytryptamine receptor 7 ligand 4-fluoro-N-[1-[2-(2-phen... 6 3
Alpha-1A adrenergic receptor and D(2) dopamine receptor ligand... 5 20
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 1
5-hydroxytryptamine receptor 7 and D(2) dopamine receptor liga... 1 0
Presenilin-1 and Presenilin-2 inhibitor AGN-PC-075BQZ family 1 2


External ID

Functional Category

Molecule Name

CFAMM00410262 CHEMBL2159322 Bioactive 5-chloro-N-[1-[2-(2-methylsulfanylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
CFAMM00410260 CHEMBL2159486 Bioactive 3-chloro-N-[1-[2-(2-methylsulfanylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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