CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11548
Family Name C-C chemokine receptor type 3 ligand 5-fluoro-1-[1-[3-(4-fluorophenyl)sulfanylpropyl]piperidin-4-yl]-2-(2,2,2-trifluoroethyl)benzimidazole family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00410349 Functional Category Bioactive
Superfamily Potassium voltage-gated channel subfamily H member 2 Ligand AZD-5438 Superfamily
Class Class 829

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Emedastine Family 5 115
Histamine H1 receptor Ligand Mizolastine Family 14 603
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
HCV NS4B protein Inhibitor Clemizole Family 2 43
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(4-e... 2 5
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Farnesyl pyrophosphate synthase Inhibitor [2-(benzoimidazol-1-... 2 16
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 4
Vascular endothelial growth factor receptor 2 and Mitogen-acti... 2 2
Nociceptin receptor and Kappa-type opioid receptor ligand 1-[1... 4 4
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 1 2
Neuropeptide Y receptor type 5 ligand 2-(3-phenylpiperidin-1-y... 6 2
Adenosine receptor A1 and Adenosine receptor A2b ligand SureCN... 2 3
Nociceptin receptor and Potassium voltage-gated channel subfam... 1 0
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... 1 0


External ID

Functional Category

Molecule Name

CFAMM00410349 CHEMBL2159766 Bioactive 5-fluoro-1-[1-[3-(4-fluorophenyl)sulfanylpropyl]piperidin-4-yl]-2-(2,2,2-trifluoroethyl)benzimidazole

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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