CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11561
Family Name Cholinesterase and Acetylcholinesterase inhibitor tacrine derivative 15h family
No. of Seeds 10 No. of Other Members 0
Family Centroid CFAMM00326010 Functional Category Bioactive
Superfamily Acetylcholinesterase and Cholinesterase Binder Superfamily 2
Class Class 3421

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Multidrug resistance protein Inhibitor Tariquidar Family 3 60
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Platelet-derived growth factor receptor alpha and Platelet-der... 2 17
Adenosine receptor A1 and Adenosine receptor A3 Ligand 4-metho... 1 16
Neuromedin-K receptor Ligand 3-methoxy-n',2-diphenylquinoline-... 14 33
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 2 30
Muscarinic acetylcholine receptor M2 and Acetylcholinesterase ... 4 24
Acetylcholinesterase and Muscarinic acetylcholine receptor M2 ... 2 7
Melanin-concentrating hormone receptor 1 and Cytochrome P450 3... 8 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(1,3-... 2 9
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Butyrylcholinesterase and Acetylcholinesterase inhibitor AGN-P... 9 24
Histone deacetylase 3 and Histone deacetylase 9 inhibitor (3S,... 1 16
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 27
Vascular endothelial growth factor receptor 2 and Vascular end... 2 52
Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hy... 3 2
Cholinesterase and Acetylcholinesterase inhibitor 5-hydroxy-7-... 5 19
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Acetylcholinesterase and Butyrylcholinesterase inhibitor (E)-3... 4 5
Cholinesterase and Acetylcholinesterase inhibitor 6-[2-methoxy... 12 6
Proto-oncogene tyrosine-protein kinase receptor Ret and Vascul... 5 14
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Platelet-activating factor receptor ligand (4R)-2-pyridin-3-yl... 1 2
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-077PI... 4 0
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-077PJ... 4 4
Inositol monophosphatase 1 and Prelamin-A/C inhibitor GNF-Pf-3... 1 5
Signal transducer and activator of transcription 1-alpha/beta ... 1 36
Smoothened homolog inhibitor N-[amino-[3-(1H-indol-2-yl)anilin... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27513 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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