CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11570
Family Name Mu-type opioid receptor and Kappa-type opioid receptor ligand N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]-3,4-dichlorobenzamide family
No. of Seeds 6 No. of Other Members 3
Family Centroid CFAMM00410475 Functional Category Bioactive
Superfamily Nalfurafine Hcl Superfamily
Class Class 66

Cousin Family NamesSeedsMembers
u-type opioid receptor ligand opiate analog Buprenorphine Family 78 234
u-type opioid receptor ligand opiate opiate analog Oxymorphone... 22 105
Nalfurafine Hcl family 33 107
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 32 30
Mu-type opioid receptor Ligand Cyprodime Family 12 8
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 6 1
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 16 10
Kappa-type opioid receptor Ligand Morphinan Cyclic Imine Analo... 20 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 28 2
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 18 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 9 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 7 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 9 2
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 8 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 7 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 0
Mu-type opioid receptor and Gastrin/cholecystokinin type B rec... 1 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00410472 CHEMBL491075 Bioactive SureCN4237860
CFAMM00410478 CHEMBL593215 Bioactive N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]-3,4-dichlorobenzamide;oxalic acid
CFAMM00410475 CHEMBL272215 Bioactive N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]-3,4-dichlorobenzamide
CFAMM00410474 CHEMBL2163538 Bioactive N-[(4R,4aS,7R,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]-3-chlorobenzamide
CFAMM00410479 CHEMBL409458 Bioactive N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]-4-chlorobenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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