CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11571
Family Name Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMBL2163577 family
No. of Seeds 6 No. of Other Members 3
Family Centroid CFAMM00388012 Functional Category Bioactive
Superfamily Prelamin-A/C and Cannabinoid receptor 2 Binder Superfamily
Class Class 1441

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Histamine H1 receptor Ligand Tranilast Family 5 125
Cystic fibrosis transmembrane conductance regulator Inhibitor ... 2 9
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Receptor tyrosine-protein kinase erbB-2 Inhibitor Mini-antibod... 1 0
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 4-(2... 4 31
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Liver carboxylesterase 1 Inhibitor 5-(trifluoromethoxy)-1h-ind... 3 12
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 16
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 8 39
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
Cathepsin S and Cathepsin L1 inhibitor arylaminoethyl amide, 8... 4 15
Lanosterol synthase inhibitor SureCN7685733 family 1 3
Cannabinoid receptor 2 ligand AGN-PC-080VZH family 3 33
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 3 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMB... 13 20
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 2 4
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Glycogen synthase kinase-3 beta inhibitor CHEMBL1940979 family 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMB... 2 2
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 5
Progesterone receptor ligand CHEMBL252850 family 2 0
Vasopressin V1a receptor and Vasopressin V2 receptor ligand AG... 4 4
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 1 1
6,8-dimethoxy-4-oxo-1H-quinoline-3-carboxylate NP ZINC00117350... 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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