CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11576
Family Name Cytochrome P450 11B1, mitochondrial and Cytochrome P450 11B2, mitochondrial inhibitor CHEMBL2163638 family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00410508 Functional Category Bioactive
Superfamily cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor 6-imidazol-1-yl-3,4-dihydro-1h-quinolin-2-one Superfamily
Class Class 715

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor Dabigatran Family 7 182
Translocator protein Inhibitor Emapunil Family 7 89
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
Class II cytokine receptor Ligand IL-10 Family 7 45
Farnesyltransferase beta subunit, putative and Protein farnesy... 20 81
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor CI-9... 3 13
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor 6-im... 2 30
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 45
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 10
Cytochrome P450 26A1 and Cytochrome P450 3A4 inhibitor AGN-PC-... 5 17
Histamine H3 receptor ligand SureCN2878688 family 8 1
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 11 2
5-hydroxytryptamine receptor 2B ligand SureCN1299437 family 6 7
Translocator protein inhibitor CHEMBL2331870 family 2 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 0
Thromboxane-A synthase inhibitor 6-chloro-3-(4-imidazol-1-ylbu... 12 21
Collagenase 3 inhibitor 4-[[6-(3-imidazol-1-ylprop-1-ynyl)-4-o... 1 1
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Substance-K receptor ligand AGN-PC-074GCM family 2 2
Melanocortin receptor 4 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00410508 CHEMBL2163638 Bioactive CHEMBL2163638
CFAMM00410511 CHEMBL2163640 Bioactive CHEMBL2163640

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26821 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543