CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM116
Family Name Sigma non-opioid intracellular receptor 1 ligand NCI60_038428 family
No. of Seeds 5 No. of Other Members 9
Family Centroid CFAMM00307327 Functional Category Bioactive
Superfamily Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21947 Superfamily
Class Class 48

Cousin Family NamesSeedsMembers
Serotonin re-uptake inhibitor tetralin derivative Sertraline f... 12 118
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Sibu... 7 127
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21... 16 89
5-hydroxytryptamine receptor 2C Ligand Lorcaserin Family 8 38
Tumor necrosis factor Inhibitor Talactoferrin Alfa Family 26 131
Zicronapine family 43 62
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 6 7
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 1
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Sodium-dependent serotonin transporter and Sodium-dependent no... 12 0
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 18 4
Sigma non-opioid intracellular receptor 1 ligand 1-[2-(3,4-dic... 8 4
Sodium-dependent serotonin transporter and Sodium-dependent do... 5 6
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 0
Transporter and Sodium-dependent dopamine transporter inhibito... 3 0
Transporter and Sodium-dependent serotonin transporter inhibit... 4 8
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 3
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 12
Sodium-dependent dopamine transporter and Sodium-dependent nor... 3 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 3 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
D(1A) dopamine receptor and D(2) dopamine receptor ligand A314... 3 1
Sigma non-opioid intracellular receptor 1 ligand NCI60_039912 ... 2 0
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 2 6
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00307324 CHEMBL101909 Bioactive (1S,2R)-N-[(3,4-dichlorophenyl)methyl]-N-methyl-2-pyrrolidin-1-ylcyclohexan-1-amine
CFAMM00307322 CHEMBL143089 Bioactive AGN-PC-003SRA
CFAMM00307328 CHEMBL134313 Bioactive 6,7-dichloro-2-(2-pyrrolidin-1-ylethyl)-3,4-dihydro-1H-isoquinoline
CFAMM00307327 CHEMBL109026 Bioactive NCI60_038428
CFAMM00307320 CHEMBL107870 Bioactive NCI60_038433

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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