CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1160
Family Name 5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic receptor ligand N-[[(3S)-2,3-dihydro-1,4-benzodioxin-3-yl]methyl]-1-(1-pyrimidin-2-ylpiperidin-4-yl)methanamine family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00294519 Functional Category Bioactive
Superfamily Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor Binder Superfamily 2
Class Class 850

Cousin Family NamesSeedsMembers
Endothelin B receptor and Endothelin-1 receptor ligand pyrimid... 22 180
Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
Hypoxia-inducible factor 1-alpha Inhibitor Hif-1alpha Family 7 107
Reverse transcriptase Inhibitor 3'thiacytidine Family 4 29
5-hydroxytryptamine receptor 1A Ligand CP-293019 Family 9 24
Deoxycytidine kinase inhibitor AGN-PC-07Z9C8 family 5 3
Deoxycytidine kinase inhibitor AGN-PC-07Z9GO family 10 2
Deoxycytidine kinase inhibitor 2-[1-[6-(2-chlorophenoxy)pyrimi... 2 3
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2J2 inhib... 1 7
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 5 45
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 8
Endothelin-1 receptor and Endothelin B receptor ligand 6-[2-(5... 3 1
Endothelin-1 receptor and Endothelin B receptor ligand 6-[2-(5... 7 0
Endothelin-1 receptor and Endothelin B receptor ligand N-(benz... 4 0
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 3
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42733 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543